Phage Therapy in Veterinary Medicine

被引:46
作者
Loponte, Rosa [1 ]
Pagnini, Ugo [1 ]
Iovane, Giuseppe [1 ]
Pisanelli, Giuseppe [1 ]
机构
[1] Univ Naples Federico II, Dept Vet Med & Anim Prod, Via Federico Delpino 1, I-80137 Naples, Italy
来源
ANTIBIOTICS-BASEL | 2021年 / 10卷 / 04期
关键词
alternative to antibiotics; bacteriophages; phage therapy; veterinary medicine; pets; CAMPYLOBACTER-JEJUNI COLONIZATION; RESISTANT PSEUDOMONAS-AERUGINOSA; REDUCE SALMONELLA COLONIZATION; IN-VIVO EFFICACY; ESCHERICHIA-COLI; STAPHYLOCOCCUS-AUREUS; BACTERIOPHAGE THERAPY; VIRULENT BACTERIOPHAGE; BROILER-CHICKENS; INFECTION;
D O I
10.3390/antibiotics10040421
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
To overcome the obstacle of antimicrobial resistance, researchers are investigating the use of phage therapy as an alternative and/or supplementation to antibiotics to treat and prevent infections both in humans and in animals. In the first part of this review, we describe the unique biological characteristics of bacteriophages and the crucial aspects influencing the success of phage therapy. However, despite their efficacy and safety, there is still no specific legislation that regulates their use. In the second part of this review, we describe the comprehensive research done in the past and recent years to address the use of phage therapy for the treatment and prevention of bacterial disease affecting domestic animals as an alternative to antibiotic treatments. While in farm animals, phage therapy efficacy perspectives have been widely studied in vitro and in vivo, especially for zoonoses and diseases linked to economic losses (such as mastitis), in pets, studies are still few and rather recent.
引用
收藏
页数:21
相关论文
共 104 条
  • [1] Taxonomy of prokaryotic viruses: 2018-2019 update from the ICTV Bacterial and Archaeal Viruses Subcommittee
    Adriaenssens, Evelien M.
    Sullivan, Matthew B.
    Knezevic, Petar
    van Zyl, Leonardo J.
    Sarkar, B. L.
    Dutilh, Bas E.
    Alfenas-Zerbini, Poliane
    Lobocka, Malgorzata
    Tong, Yigang
    Brister, James Rodney
    Switt, Andrea I.
    Klumpp, Jochen
    Aziz, Ramy Karam
    Barylski, Jakub
    Uchiyama, Jumpei
    Edwards, Rob A.
    Kropinski, Andrew M.
    Petty, Nicola K.
    Clokie, Martha R. J.
    Kushkina, Alla I.
    Morozova, Vera V.
    Duffy, Siobain
    Gillis, Annika
    Rumnieks, Janis
    Kurtboke, Ipek
    Chanishvili, Nina
    Goodridge, Lawrence
    Wittmann, Johannes
    Lavigne, Rob
    Jang, Ho Bin
    Prangishvili, David
    Enault, Francois
    Turner, Dann
    Poranen, Minna M.
    Oksanen, Hanna M.
    Krupovic, Mart
    [J]. ARCHIVES OF VIROLOGY, 2020, 165 (05) : 1253 - 1260
  • [2] Prophylactic Bacteriophage Administration More Effective than Post-infection Administration in Reducing Salmonella enterica serovar Enteritidis Shedding in Quail
    Ahmadi, Mosab
    Torshizi, M. Amir Karimi
    Rahimi, Shaban
    Dennehy, John J.
    [J]. FRONTIERS IN MICROBIOLOGY, 2016, 7
  • [3] Bacteriophage therapy to reduce Salmonella colonization of broiler chickens
    Atterbury, R. J.
    Van Bergen, M. A. P.
    Ortiz, F.
    Lovell, M. A.
    Harris, J. A.
    De Boer, A.
    Wagenaar, J. A.
    Allen, V. M.
    Barrow, P. A.
    [J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2007, 73 (14) : 4543 - 4549
  • [4] Correlation of Campylobacter bacteriophage with reduced presence of hosts in broiler chicken ceca
    Atterbury, RJ
    Dillon, E
    Swift, C
    Connerton, PL
    Frost, JA
    Dodd, CER
    Rees, CED
    Connerton, IF
    [J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2005, 71 (08) : 4885 - 4887
  • [5] Use of lytic bacteriophage for control of experimental Escherichia coli septicemia and meningitis in chickens and calves
    Barrow, P
    Lovell, M
    Berchieri, A
    [J]. CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 1998, 5 (03) : 294 - 298
  • [6] Bacteriophage Treatment Reduces Salmonella Colonization of Infected Chickens
    Borie, C.
    Albala, I.
    Sanchez, P.
    Sanchez, M. L.
    Ramirez, S.
    Navarro, C.
    Morales, M. A.
    Retamales, J.
    Robeson, J.
    [J]. AVIAN DISEASES, 2008, 52 (01) : 64 - 67
  • [7] Burrowes B, 2011, EXPERT REV ANTI-INFE, V9, P775, DOI [10.1586/ERI.11.90, 10.1586/eri.11.90]
  • [8] Sublethal streptomycin concentrations and lytic bacteriophage together promote resistance evolution
    Cairns, Johannes
    Becks, Lutz
    Jalasvuori, Matti
    Hiltunen, Teppo
    [J]. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2017, 372 (1712)
  • [9] Carlton Richard M., 1999, Archivum Immunologiae et Therapiae Experimentalis, V47, P267
  • [10] Bacteriophage therapy to reduce Campylobacter jejuni colonization of broiler chickens
    Carrillo, CL
    Atterbury, RJ
    El-Shibiny, A
    Connerton, PL
    Dillon, E
    Scott, A
    Connerton, IF
    [J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2005, 71 (11) : 6554 - 6563