Solubility of Flurbiprofen in CO2 and CO2 + Methanol

被引：8

作者：

Chin, Gui Jin ^{[1
]}

Chee, Zi Hui ^{[1
]}

Chen, Wenda ^{[1
]}

Rajendran, Arvind ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Chem & Biomed Engn, Singapore 637459, Singapore

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2010年 / 55卷 / 04期

关键词：

ENANTIOSEPARATION; CHROMATOGRAPHY; SEPARATION; EQUATION; STATE;

D O I：

10.1021/je900674t

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

The solubility of (RS)-2-(2-fluorobipheny1-4-yl)propanoic acid (flurbiprofen) in supercritical carbon dioxide and in a mixed solvent consistma of carbon dioxide and methanol at (303.15 and 313 15) K between the pressures of (10.0 and 20 0) MPa is reported The solubilities were measured using a direct visualization technique The experimental data is described using the Peng Robinson equation of state (PR EoS) together with a one-parameter van del Waals mixing rule

引用

页码：1542 / 1546

页数：5

共 17 条

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