Solubility of Flurbiprofen in CO2 and CO2 + Methanol

被引：8
作者：
Chin, Gui Jin [1 ]
Chee, Zi Hui [1 ]
Chen, Wenda [1 ]
Rajendran, Arvind [1 ]
机构：
[1] Nanyang Technol Univ, Sch Chem & Biomed Engn, Singapore 637459, Singapore
来源：
JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2010年 / 55卷 / 04期
关键词：
ENANTIOSEPARATION; CHROMATOGRAPHY; SEPARATION; EQUATION; STATE;
D O I：
10.1021/je900674t
中图分类号：
O414.1 [热力学];
学科分类号：
摘要：
The solubility of (RS)-2-(2-fluorobipheny1-4-yl)propanoic acid (flurbiprofen) in supercritical carbon dioxide and in a mixed solvent consistma of carbon dioxide and methanol at (303.15 and 313 15) K between the pressures of (10.0 and 20 0) MPa is reported The solubilities were measured using a direct visualization technique The experimental data is described using the Peng Robinson equation of state (PR EoS) together with a one-parameter van del Waals mixing rule
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页码：1542 / 1546
页数：5
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