Iron-Catalyzed Sulfenylation of Indoles with Disulfides Promoted by a Catalytic Amount of Iodine

被引：150

作者：

Fang, Xiao-Li ^{[1
]}

Tang, Ri-Yuan ^{[1
]}

Zhong, Ping ^{[1
]}

Li, Jin-Heng ^{[1
]}

机构：

[1] Wenzhou Univ, Coll Chem & Mat Sci, Wenzhou 325035, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2009年 / 24期

基金：

中国国家自然科学基金;

关键词：

iron(III) fluoride; sulfenylation; indoles; disulfides; sulfenylindoles; iodine; 2ND SULFENYLATION; BIOLOGICAL EVALUATION; DERIVATIVES; 3-SULFENYL; INHIBITORS; MECHANISM;

D O I：

10.1055/s-0029-1217037

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Selective sulfenylation of indoles with disulfides using iron(III) fluoride combined with iodine has been developed for the synthesis of sulfenylindoles. In the presence of iron(III) fluoride and iodine, a variety of disulfides underwent the reaction with indoles selectively to afford the corresponding sulfenylindoles in good to excellent yields. Moreover, reactions of indoles with 1,2-diphenyldiselane were also conducted under the same conditions, which smoothly afforded 3-selenylindoles in good yields.

引用

页码：4183 / 4189

页数：7

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