Hormonal and genetic risk factors for breast cancer

被引：9
作者：
Clamp, A [1 ]
Danson, S [1 ]
Clemons, M [1 ]
机构：
[1] Toronto Sunnybrook Reg Canc Ctr, Dept Med Oncol, Toronto, ON M4N 3M5, Canada
来源：
SURGEON-JOURNAL OF THE ROYAL COLLEGES OF SURGEONS OF EDINBURGH AND IRELAND | 2003年 / 1卷 / 01期
关键词：
breast cancer; hormones; genetic; risk factors;
D O I：
10.1016/S1479-666X(03)80005-7
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Breast cancer is a major cause of female morbidity and mortality worldwide. In this review, we discuss the hormonal and genetic risk factors associated with breast cancer development and describe the currently available models for predicting an individual woman's risk. We highlight three more sophisticated surrogate markers of life-time oestrogen exposure (plasma oestradiol, mammographic breast density, bone mineral density) and propose that these may be used to improve estimates of a woman's absolute risk
引用
收藏
页码：23 / 31
页数：9
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