Excited-state proton transfer reactions of 10-hydroxycamptothecin

被引：56

作者：

Solntsev, KM ^{[1
]}

Sullivant, EN

Tolbert, LM

Ashkenazi, S

Leiderman, P

Huppert, D

机构：

[1] Georgia Inst Technol, Sch Chem & Biochem, Atlanta, GA 30332 USA

[2] Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 39期

关键词：

D O I：

10.1021/ja047821e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Time-resolved and steady-state emission characterization of 10-hydroxycamptothecin reveals a rich but less complex proton-transfer behavior than its parent hydroxyquinoline. The electronic effect of the additional electron-withdrawing ring makes the excited-state both less basic and more acidic than the parent and adds to the class of high-acidity excited-state proton donors in photochemistry and photobiology.

引用

页码：12701 / 12708

页数：8

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