[1] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Physiol, Singapore 117595, Singapore
[2] NUS Grad Sch Integrat Sci & Engn, Singapore, Singapore
[3] Neurobiol Aging Program, Singapore, Singapore
[4] Natl Inst Neurosci, Singapore, Singapore
[5] Kyoto Univ, Grad Sch Engn, Dept Synthet Chem & Biol Chem, Kyoto, Japan