Synthesis and crystal structure of 3,7,7-trimethyl-1-phenyl-4-(3-nitrophenyl)-4,5,6,7,8,9-hexahydro-1H-pyrazolo [3,4-b]quinoline-5(6H)-one

被引：0
作者：
Xu, JN [1 ]
Tu, SJ [1 ]
Jiang, H [1 ]
Zhang, JP [1 ]
Zhu, XT [1 ]
Wang, Q [1 ]
机构：
[1] Xuzhou Normal Univ, Dept Chem, Key Lab Biotechnol Med Plant, Jiangsu 221009, Peoples R China
来源：
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY | 2005年 / 24卷 / 02期
关键词：
pyrazole; quinoline; synthesis; microwave irradiation; crystal structure;
D O I：
暂无
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The title compound (C25H24N4O3) has been. prepared by the cyclocondensation of 5-amino-3-methyl-1-phenypyrazol, m-nitrobenaldehyde and dimedone in glycol under microwave irradiation without catalyst. The crystal structure was determined by single-crystal X-ray diffraction to be orthorhombic, space group Pbca with a = 16.3331(10), b = 13.8329(9), c = 19.4163(12) Angstrom, V =4386.8(5) Angstrom(3), Z=8, D-c = 1.298 g/cm(3), mu = 0.087 mm(-1), F(000) = 1808, M-r = 428.48, the final R = 0.0519 and wR = 0.1019. X-ray analysis revealed that the pyridine ring is of boat conformation and the six-membered ring fused with it adopts twist boat conformation.
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页码：209 / 213
页数：5
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