FRAILTY AND SARCOPENIA: THE NEW GERIATRIC GIANTS

被引：1

作者：

Morley, John E. ^{[1
,2
]}

机构：

[1] St Louis Univ, Sch Med, Div Geriatr Med, 1402 S Grand Blvd,M238, St Louis, MO 63104 USA

[2] St Louis Univ, Sch Med, Div Endocrinol, St Louis, MO 63104 USA

来源：

REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATION | 2016年 / 68卷 / 02期

关键词：

Frailty; Sarcopenia; Geriatrics; Screening tools; Aging; SUPPLEMENTATION INCREASES MUSCLE; VITAMIN-D SUPPLEMENTATION; HUMAN GROWTH-HORMONE; DECREASES FAT MASS; PHYSICAL FUNCTION; DOUBLE-BLIND; OLDER-ADULTS; COGNITIVE IMPAIRMENT; ELDERLY-PEOPLE; TESTOSTERONE REPLACEMENT;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In the last decade, it has become clear that older persons who are frail or sarcopenic have very high rates of functional deterioration, hospitalization, and death. Recently, it has become recognized that simple screening questionnaires, e.g., the FRAIL and SARC-F, perform as well as more complex testing for the physical phenotype screen and sarcopenia. In this article, we provide a simple algorithm for the management of frailty. The multiple factors responsible for the pathogenesis of sarcopenia are reviewed, focusing on the importance of age-associated loss of motor units innervating muscle. Management of sarcopenia includes resistance exercise, leucine-enriched protein, and vitamin D. A number of newer drugs are under development. General practitioners should be encouraged to screen for frailty and sarcopenia in older persons.

引用

页码：59 / 67

页数：9

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