A turn-on PET fluorescence sensor for imaging Cu2+ in living cells

被引:56
|
作者
He, Guangjie [2 ]
Zhao, Xiuwen [2 ]
Zhang, Xiaolin [2 ]
Fan, Hongjun [1 ]
Wu, Shuo [2 ]
Li, Huaqiang [2 ]
He, Cheng [2 ]
Duan, Chunying [2 ]
机构
[1] Dalian Inst Chem Phys, State Key Lab Mol React Dynam, Dalian 116023, Peoples R China
[2] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116012, Peoples R China
基金
中国国家自然科学基金;
关键词
CU(II) ION; DESIGN; FLUOROIONOPHORE; COPPER; DERIVATIVES; RECEPTOR; CHEMODOSIMETER; CHEMOSENSORS; FLUOROPHORE; MECHANISMS;
D O I
10.1039/c0nj00132e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
By the incorporation of coumarin fluorophores within the benzyldihydrazone moiety and by carefully adjusting the redox potential of the. uorophore and its excited state energy, one of the brightest Cu2+-binding sensors in aqueous media was achieved and could be used for the detection of Cu2+ in living cells.
引用
收藏
页码:1055 / 1058
页数:4
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