Use of ultrasound contrast agents for gene or drug delivery in cardiovascular medicine

被引：215
作者：
Bekeredjian, R
Grayburn, PA
Shohet, RV
机构：
[1] Univ Texas, SW Med Ctr, Dept Internal Med, Div Cardiol, Dallas, TX USA
[2] Baylor Univ, Med Ctr, Dallas, TX USA
来源：
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2005年 / 45卷 / 03期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/j.jacc.2004.08.067
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The clinical utility of ultrasound contrast agents has been established in diagnostic echocardiography. Recently, the use of such agents has been promoted for transport and delivery of various bioactive substances, thus providing a technique for non-invasive gene therapy and organ-specific drug delivery. In this review, we give a critical update of published studies using ultrasound contrast agents for therapeutic use. We discuss the potential applications and limitations of this technique and suggest future applications in cardiovascular medicine. (C) 2005 by the American College of Cardiology Foundation.
引用
收藏
页码：329 / 335
页数：7
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