Designed evolution of artificial metalloenzymes: protein catalysts made to order

被引:46
|
作者
Creus, Marc
Ward, Thomas R.
机构
[1] Univ Neuchatel, Dept Chem, CH-2009 Neuchatel, Switzerland
[2] Univ Neuchatel, Dept Cellular & Mol Biol, CH-2009 Neuchatel, Switzerland
关键词
D O I
10.1039/b702068f
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Artificial metalloenzymes based on biotin-streptavidin technology, a "fusion" of chemistry and biology, illustrate how asymmetric catalysts can be improved and evolved using chemogenetic approaches.
引用
收藏
页码:1835 / 1844
页数:10
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