Pediatric hypervirulent Klebsiella pneumoniae septic arthritis

被引:14
作者
Kishibe, Shun [1 ]
Okubo, Yusuke [1 ,6 ]
Morino, Saeko [2 ]
Hirotaki, Shintaro [2 ]
Tame, Tomoyuki [4 ]
Aoki, Kotaro [5 ]
Ishii, Yoshikazu [5 ]
Ota, Norikazu [3 ]
Shimomura, Satoshi [3 ]
Sakakibara, Hiroshi [1 ]
Terakawa, Toshiro [1 ]
Horikoshi, Yuho [2 ]
机构
[1] Tokyo Metropolitan Childrens Med Ctr, Dept Gen Pediat, Tokyo, Japan
[2] Tokyo Metropolitan Childrens Med Ctr, Dept Pediat, Div Infect Dis, Tokyo, Japan
[3] Tokyo Metropolitan Childrens Med Ctr, Div Orthoped, Tokyo, Japan
[4] Tokyo Metropolitan Childrens Med Ctr, Div Lab, Tokyo, Japan
[5] Toho Univ, Sch Med, Dept Microbiol & Infect Dis, Tokyo, Japan
[6] Harvard Sch Publ Hlth, Dept Quantitat Methods, Boston, MA USA
关键词
bacterial translocation; hypermucoviscosity; hypervirulent Klebsiella pneumoniae; septic arthritis; string test; LIVER-ABSCESS; HYPERMUCOVISCOSITY; ASSOCIATION; CHILDREN; INFANTS;
D O I
10.1111/ped.12806
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Cases of infection with hypervirulent Klebsiella pneumoniae are gradually increasing in number, and cause life-threatening community-acquired infection even in immunocompetent patients. A 14-year-old boy developed septic hip arthritis due to hypervirulent K. pneumoniae (sequence type 23, serotype K1, magA positive). The patient initially seemed to have been successfully treated with antibiotics and surgical intervention, but septic arthritis developed into osteomyelitis of the femoral head and myositis, which required long-term antibiotic therapy and additional surgical intervention. This is the first pediatric case of hypervirulent K. pneumoniae septic hip arthritis. Treatment plans should mainly consist of antibiotic therapy and surgical intervention. Clinicians, even pediatricians, in developed countries should be aware of the increasing incidence of hypervirulent Klebsiella pneumoniae infection.
引用
收藏
页码:382 / 385
页数:5
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