A role for cytokine measurement in therapeutic monitoring of immunosuppressive drugs following lung transplantation

被引:29
作者
Corris, PA [1 ]
Kirby, JA
机构
[1] Newcastle Univ, Sch Clin Med Sci, Appl Immunobiol & Transplantat Res Grp, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England
[2] Freeman Rd Hosp, Newcastle Upon Tyne NE7 7DN, Tyne & Wear, England
关键词
cytokine; therapeutic monitoring; immunosuppression; lung transplantation;
D O I
10.1111/j.1365-2249.2005.02711.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页码:176 / 178
页数:3
相关论文
共 23 条
[1]   Transplant immunobiology: A crucial role for heparan sulfate glycosaminoglycans? [J].
Ali, S ;
Hardy, LA ;
Kirby, JA .
TRANSPLANTATION, 2003, 75 (11) :1773-1782
[2]   Assessment of mechanisms of action of immunosuppressive drugs using novel whole blood assays [J].
Barten, MJ ;
Gummert, JF ;
van Gelder, T ;
Shorthouse, R ;
Morris, RE .
TRANSPLANTATION PROCEEDINGS, 2001, 33 (03) :2119-2120
[3]   Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: inhibition by immunosuppressive drugs in vitro [J].
Barten, MJ ;
Gummert, JF ;
van Gelder, T ;
Shorthouse, R ;
Morris, RE .
JOURNAL OF IMMUNOLOGICAL METHODS, 2001, 253 (1-2) :95-112
[4]   CYTOKINE GENE-EXPRESSION - ANALYSIS USING NORTHERN BLOTTING, POLYMERASE CHAIN-REACTION AND INSITU HYBRIDIZATION [J].
DALLMAN, MJ ;
MONTGOMERY, RA ;
LARSEN, CP ;
WANDERS, A ;
WELLS, AF .
IMMUNOLOGICAL REVIEWS, 1991, 119 :163-179
[5]   Elevated levels of interleukin-8 in donor lungs is associated with early craft failure after lung transplantation [J].
Fisher, AJ ;
Donnelly, SC ;
Hirani, N ;
Haslett, C ;
Strieter, RM ;
Dark, JH ;
Corris, PA .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2001, 163 (01) :259-265
[6]   VARIATION IN EXPRESSION OF ENDOTHELIAL ADHESION MOLECULES IN PRETRANSPLANT AND TRANSPLANTED KIDNEYS - CORRELATION WITH INTRAGRAFT EVENTS [J].
FUGGLE, SV ;
SANDERSON, JB ;
GRAY, DWR ;
RICHARDSON, A ;
MORRIS, PJ .
TRANSPLANTATION, 1993, 55 (01) :117-123
[7]  
Heeger PS, 1999, J IMMUNOL, V163, P2267
[8]   Intracellular cytokines in blood T cells in lung transplant patients - a more relevant indicator of immunosuppression than drug levels [J].
Hodge, G ;
Hodge, S ;
Reynolds, P ;
Holmes, M .
CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2005, 139 (01) :159-164
[9]   C2 monitoring strategy for optimising cyclosporin immunosuppression from the neoral®1 formulation [J].
Levy, GA .
BIODRUGS, 2001, 15 (05) :279-290
[10]   HYPOTHESIS - WHY DO SO MANY LYMPHOCYTES RESPOND TO MAJOR HISTOCOMPATIBILITY ANTIGENS [J].
MATZINGER, P ;
BEVAN, MJ .
CELLULAR IMMUNOLOGY, 1977, 29 (01) :1-5