Influence of different surfactants on development of nanoemulsion containing fixed oil from an Amazon palm species

被引：11

作者：

Almeida, Fernanda ^{[1
]}

Correa, Marcos ^{[1
]}

Melero Zaera, Ana ^{[2
]}

Garrigues, Teresa ^{[2
]}

Isaac, Vera ^{[1
]}

机构：

[1] Sao Paulo State Univ Unesp, Sch Pharmaceut Sci, Araraquara, SP, Brazil

[2] Univ Valencia, Dept Pharm & Pharmaceut Technol, Valencia, Spain

来源：

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS | 2022年 / 643卷

关键词：

Nanoemulsion; Surfactants; Tucuma similar to; Amazon; Low energy method; INDUCED DIABETIC MICE; LOW-ENERGY FORMATION; M. PULP OIL; ASTROCARYUM-VULGARE; NANO-EMULSIONS; PHASE-BEHAVIOR; ANTIINFLAMMATORY PROPERTIES; EDIBLE NANOEMULSIONS; IN-VITRO; TEMPERATURE;

D O I：

10.1016/j.colsurfa.2022.128721

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Astrocaryum vulgare is an Amazon palm species, popularly known as tucuma. A. vulgare oil has diverse biological purposes, but low solubility in water. Nanoemulsions provide a solution to this problem. This study aimed to evaluate the influence of different surfactants on the development of nanoemulsions. To determine the hydrophilic-lipophilic balance (HLB), the influence of different surfactants on nanoemulsification was determined, the region of nanoemulsion formation on the pseudo-ternary phase diagram was analyzed, nano emulsions were characterized, and the best candidate was subjected to stability assessment. The HLB was 14, and PPG-5-Ceteth-20 and sorbitan oleate were selected as surfactants. The nanoemulsion had a droplet size of 174.1 nm, a polydispersity index of 0.295, and a zeta potential of 20.7. A. vulgare oil is used in the Amazon for countless pharmaceutical applications. We demonstrate the impact of the chemical structure of surfactants, resulting in the formation of nanoemulsions containing A. vulgare oil.

引用

页数：10

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