Synthesis, characterization and in vivo anthelmintic activity of some novel N-Mannich bases of benzimidazoles

被引：0

作者：

Murti, Yogesh ^{[1
]}

Arora, Rashmi ^{[1
]}

Pathak, Devender ^{[1
]}

机构：

[1] Rajiv Acad Pharm, Dept Pharmaceut Chem, Mathura 281001, Uttar Pradesh, India

来源：

JOURNAL OF THE INDIAN CHEMICAL SOCIETY | 2010年 / 87卷 / 05期

关键词：

Mannich bases; benzimidazole; anthelmintic activity;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

As a part of ongoing efforts towards finding novel anthelmintic agents, N-Mannich bases of benzimidazole were obtained by condensation of substituted secondary amines and aldehyde in ethanol. These compounds were identified on the basis of melting point range, R-f values, elemental analysis, IR and H-1 NMR spectral analysis. The synthetic work is fruitless without performing biological activities, so the newly synthesized compounds were screened for pharmacological activity. Anthelmintic activity was carried out against Eudrilus species of earthworms.

引用

页码：627 / 631

页数：5

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