Analytical solution of steady state current at a microdisk biosensor

被引：19

作者：

Eswari, A. ^{[1
]}

Rajendran, L. ^{[1
]}

机构：

[1] Madura Coll, Dept Math, Madurai 625011, Tamil Nadu, India

来源：

JOURNAL OF ELECTROANALYTICAL CHEMISTRY | 2010年 / 641卷 / 1-2期

关键词：

Amperometry; Microdisk biosensors; Michaelis-Menten kinetics; Mathematical modeling; Enzyme electrode; HOMOTOPY PERTURBATION METHOD; ELECTRODES;

D O I：

10.1016/j.jelechem.2010.01.015

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The steady state concentration and current occurring at a microdisk enzyme electrode when a product from an immobilized enzyme reacts with the electrode is derived. A closed form of an analytical expression of concentration for the full range of enzyme activities has been derived. A simple approximate analytical expression of current in terms of all dimensionless parameters for film thickness r(1)/r(0) and enzyme kinetic chi r(0) for all values of Michaelis-Menten constant is also reported. Available limiting case results are compared with our results and are found to be in good agreement. Crown Copyright (C) 2010 Published by Elsevier B.V. All rights reserved.

引用

页码：35 / 44

页数：10

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