Antithyroid antibodies in the CSF - Their role in the pathogenesis of Hashimoto's encephalopathy

被引：138

作者：

Ferracci, F

Moretto, G

Candeago, RM

Cimini, N

Conte, F

Gentile, M

Papa, N

Carnevale, A

机构：

[1] Osped San Martino Genova, Dept Neurol, I-32100 Belluno, Italy

[2] Osped San Martino Genova, Lab Med, I-32100 Belluno, Italy

[3] Osped S Giacomo, Dept Neurol, Rome, Italy

来源：

NEUROLOGY | 2003年 / 60卷 / 04期

关键词：

D O I：

10.1212/01.WNL.0000048660.71390.C6

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Antithyroid antibodies and circulating immune complexes (CIC) were found in the CSF of six patients with Hashimoto's encephalopathy (HE) but not in the CSF of 21 controls. The synthesis of autoantibodies and CIC was intrathecal and their titers were independent of the patients' clinical status or therapy. Their presence in the CSF of patients with acute or subacute encephalopathy may be useful in diagnosing HE.

引用

页码：712 / 714

页数：3

共 7 条

[1] Myelopathy associated with Hashimoto's disease
Azuma, T
Uemichi, T
Funauchi, M
Doi, S
Matsubara, T
[J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2000, 68 (05) : 681 - 682
[2] Autoimmune thyroiditis and a rapidly progressive dementia: Global hypoperfusion on SPECT scanning suggests a possible mechanism
Forchetti, CM
Katsamakis, G
Garron, DC
[J]. NEUROLOGY, 1997, 49 (02) : 623 - 626
[3] LATINVILLE D, 1985, REV NEUROL, V141, P55
[4] Hashimoto encephalopathy: A brainstem vasculitis?
Nolte, KW
Unbehaun, A
Sieker, H
Kloss, TM
Paulus, W
[J]. NEUROLOGY, 2000, 54 (03) : 769 - 770
[5] Hashimoto's encephalitis as a differential diagnosis of Creutzfeldt-Jakob disease
Seipelt, M
Zerr, I
Nau, R
Mollenhauer, B
Kropp, S
Steinhoff, BJ
Wilhelm-Gössling, C
Bamberg, C
Janzen, RWC
Berlit, P
Manz, F
Felgenhauer, K
Poser, S
[J]. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1999, 66 (02) : 172 - 176
[6] HASHIMOTO ENCEPHALOPATHY - A STEROID-RESPONSIVE DISORDER ASSOCIATED WITH HIGH ANTITHYROID ANTIBODY-TITERS - REPORT OF 5 CASES
SHAW, PJ
WALLS, TJ
NEWMAN, PK
CLELAND, PG
CARTLIDGE, NEF
[J]. NEUROLOGY, 1991, 41 (02) : 228 - 233
[7] Shibata N, 1992, Rinsho Shinkeigaku, V32, P191

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