Research Progress of Stimuli Responsive Nanocarriers in Diagnosis and Treatment of Cancer

被引:0
作者
Tian Hao [1 ,2 ]
Zhao Peng-Fei [2 ]
Zheng Ming-Bin [1 ,2 ]
Ma Ai-Qing [1 ,2 ]
Luo Zhen-Yu [2 ]
Chen Shi-Chun [1 ]
Lu Cheng-Yu [1 ]
Cai Lin-Tao [2 ]
机构
[1] Guangdong Med Univ, Dongguan Key Lab Drug Design & Formulat Technol, Key Lab Nanomed, Dongguan 523808, Peoples R China
[2] Chinese Acad Sci, Shenzhen Inst Adv Technol, Guangdong Key Lab Nanomed, CAS Key Lab Hlth Informat, Shenzhen 518055, Peoples R China
基金
中国国家自然科学基金;
关键词
stimuli responsive; drug release; nanocarriers; drug delivery; cancer; MESOPOROUS SILICA NANOPARTICLES; DRUG-DELIVERY SYSTEM; POLYMERIC NANOPARTICLES; SIRNA DELIVERY; PH; RELEASE; DOXORUBICIN; MICELLES; CELLS; NANOMEDICINE;
D O I
10.16476/j.pibb.2017.0393
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Stimuli responsive nanocarriers as nano-intelligent drug delivery system could make corresponding change in structure and physicochemical properties for response to external stimulus. Take the advantages of avoiding premature drug release and improving the drug concentration in the lesion, they have become a focus in diagnosis and treatment of cancer and were widely used to control drug delivery and release. Based on the temperature, magnetic field, ultrasonic, light, pH and other endogenous and endogenous stimulus, we reviewed the recent research development of stimuli responsive nanocarriers in the field of tumor diagnosis and treatment in this paper.
引用
收藏
页码:593 / 600
页数:8
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