Proposal for a new subtype of the zoonotic genotype 3 Hepatitis E virus: HEV-31

被引：21

作者：

De Sabato, Luca ^{[1
,2
]}

Lemey, Philippe ^{[3
]}

Vranken, Bram ^{[3
]}

Bonfanti, Lebana ^{[4
]}

Ceglie, Letizia ^{[4
]}

Vaccari, Gabriele ^{[1
]}

Di Bartolo, Ilaria

机构：

[1] Ist Super Sanita, Dept Food Safety Nutr & Vet Publ Hlth, Viale Regina Elena 299, I-00161 Rome, Italy

[2] Univ Rome Tre, Dept Sci, Viale Guglielmo Marconi 446, I-00146 Rome, Italy

[3] Univ Leuven, KU Leuven, Dept Microbiol & Immunol, Rega Inst, Herestr 49, B-3000 Leuven, Belgium

[4] Ist Zooprofilatt Sperimentale Venezie, Viale Univ 10, I-35020 Legnaro, PD, Italy

来源：

VIRUS RESEARCH | 2018年 / 248卷

关键词：

Hepatitis E virus; Complete genome; Next generation sequencing; Genotype; 3; Subtype; Swine; SWINE; SEQUENCES; FARM;

D O I：

10.1016/j.virusres.2018.02.010

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The near-complete genomic sequences of two hepatitis E virus (HEV) strains, detected from feces of infected pigs, were obtained. Phylogenetic analysis and p-distance comparisons of the complete coding regions showed a close relationship to the French swine strain FR-SHEV3c-like detected in 2006 (p-distance value 0.101), belonging to HEV-3 but not assigned to any known subtype. The three HEV sequences showed, relatively high nucleotide distances (p-distance > 0.129) compared to the other defined HEV subtype references and unclassified strains. The HEV classification criteria and the high sequence similarity suggest that these strains can be assigned to a putative novel subtype of genotype 3, HEV-31.

引用

页码：1 / 4

页数：4

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