Biomedical and biotechnological applications of elastin-like polypeptides

被引：73
作者：
Simnick, Andrew J. [1 ]
Lim, Dong Woo [1 ]
Chow, Dominic [1 ]
Chilkoti, Ashutosh [1 ]
机构：
[1] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA
来源：
POLYMER REVIEWS | 2007年 / 47卷 / 01期
关键词：
elastin-like polypeptide; drug delivery; tissue engineering; protein purification; biosensors; genetically-encoded polymers;
D O I：
10.1080/15583720601109594
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Elastin-like polypeptides (ELPs) are a unique class of genetically encoded biopolymers with tunable thermosensitivity and biocompatibility. This review provides an introduction to ELPs and an overview of their design and synthesis. It also discusses applications of these polypeptides for drug delivery, tissue engineering, protein purification, and biosensing.
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收藏
页码：121 / 154
页数：34
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