CANCER GENOMICS Copy number signatures in ovarian cancer

被引:3
|
作者
Shah, Sohrab P. [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Dept Epidemiol & Biostat, Computat Oncol, 1275 York Ave, New York, NY 10021 USA
关键词
D O I
10.1038/s41588-018-0212-y
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A new study uncovers novel copy number signatures in ovarian cancer genomes. This work sheds light on mutational processes driving ovarian cancer, reveals the distribution of copy number features across the patient population and identifies new genomic properties related to treatment response.
引用
收藏
页码:1208 / 1209
页数:3
相关论文
共 50 条
  • [1] Copy number signatures in ovarian cancer
    Sohrab P. Shah
    Nature Genetics, 2018, 50 : 1208 - 1209
  • [2] Characterizing HRD in ovarian cancer: Insights from copy number signatures
    Hawari, Aliah
    Tapinos, Avraam
    Kramer, Claire J.
    Gruber, Andreas J.
    Houlston, Richard
    Brenton, James
    Wedge, David
    CANCER RESEARCH, 2024, 84 (06)
  • [3] Signatures of copy number alterations in human cancer
    Steele, Christopher D.
    Abbasi, Ammal
    Islam, S. M. Ashiqul
    Bowes, Amy L.
    Khandekar, Azhar
    Haase, Kerstin
    Hames-Fathi, Shadi
    Ajayi, Dolapo
    Verfaillie, Annelien
    Dhami, Pawan
    McLatchie, Alex
    Lechner, Matt
    Light, Nicholas
    Shlien, Adam
    Malkin, David
    Feber, Andrew
    Proszek, Paula
    Lesluyes, Tom
    Mertens, Fredrik
    Flanagan, Adrienne M.
    Tarabichi, Maxime
    Van Loo, Peter
    Alexandrov, Ludmil B.
    Pillay, Nischalan
    NATURE, 2022, 606 (7916) : 984 - +
  • [4] Signatures of copy number alterations in human cancer
    Christopher D. Steele
    Ammal Abbasi
    S. M. Ashiqul Islam
    Amy L. Bowes
    Azhar Khandekar
    Kerstin Haase
    Shadi Hames-Fathi
    Dolapo Ajayi
    Annelien Verfaillie
    Pawan Dhami
    Alex McLatchie
    Matt Lechner
    Nicholas Light
    Adam Shlien
    David Malkin
    Andrew Feber
    Paula Proszek
    Tom Lesluyes
    Fredrik Mertens
    Adrienne M. Flanagan
    Maxime Tarabichi
    Peter Van Loo
    Ludmil B. Alexandrov
    Nischalan Pillay
    Nature, 2022, 606 : 984 - 991
  • [5] On the Minimum Copy Number Generation Problem in Cancer Genomics
    Qingge, Letu
    He, Xiaozhou
    Liu, Zhihui
    Zhu, Binhai
    ACM-BCB'18: PROCEEDINGS OF THE 2018 ACM INTERNATIONAL CONFERENCE ON BIOINFORMATICS, COMPUTATIONAL BIOLOGY, AND HEALTH INFORMATICS, 2018, : 260 - 269
  • [6] Copy number alteration signatures as biomarkers in cancer: a review
    Doran, Conor Giles
    Pennington, Stephen R.
    BIOMARKERS IN MEDICINE, 2022, 16 (05) : 371 - 386
  • [7] The repertoire of copy number alteration signatures in human cancer
    Tao, Ziyu
    Wang, Shixiang
    Wu, Chenxu
    Wu, Tao
    Zhao, Xiangyu
    Ning, Wei
    Wang, Guangshuai
    Wang, Jinyu
    Chen, Jing
    Diao, Kaixuan
    Chen, Fuxiang
    Liu, Xue-Song
    BRIEFINGS IN BIOINFORMATICS, 2023, 24 (02)
  • [8] An overview of mutational and copy number signatures in human cancer
    Steele, Christopher D.
    Pillay, Nischalan
    Alexandrov, Ludmil B.
    JOURNAL OF PATHOLOGY, 2022, 257 (04): : 454 - 465
  • [9] Identification of distinct global Copy Number Alteration signatures in different human cancer types and mouse models with the UCSC Cancer Genomics Browser
    Wang, Ting
    Szeto, Christopher
    Zhu, Jingchu
    Sanborn, J. Zachary
    Benz, Stephen
    Haussler, David
    CANCER RESEARCH, 2009, 69
  • [10] Prognostic Relevance of Copy Number Losses in Ovarian Cancer
    Jemma, Andrea
    Ardizzoia, Alessandra
    Redaelli, Serena
    Bentivegna, Angela
    Lavitrano, Marialuisa
    Conconi, Donatella
    GENES, 2024, 15 (11)