Early Goal Directed Therapy Strategy for Sepsis Management

Sepsis and septic shock are associated with high morbidity and mortality outcomes. Therefore, early identification and a proper intervention provide better outcomes. The method to develop the identification and intervention is usually released in guidelines. The Early Goal Directed Therapy (EGDT), which is operative based on River's study in the beginning of this century stands out. Although there have been subsequent studies which disapprove this study, the EGDT concept persists in the Surviving Sepsis guidelines and in the current clinical practice. As the medical knowledge evolve, static measures have been abandoned and other measures as early fluid an antibiotic administration, lactate clearance and a proper and continuous patient assessment has been stablished.