High-speed fiber-based polarization-sensitive optical coherence tomography of in vivo human skin

被引:264
作者
Saxer, CE [1 ]
de Boer, JF [1 ]
Park, BH [1 ]
Zhao, YH [1 ]
Chen, ZP [1 ]
Nelson, JS [1 ]
机构
[1] Univ Calif Irvine, Beckman Laser Inst & Med Clin, Irvine, CA 92612 USA
关键词
D O I
10.1364/OL.25.001355
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
A high-speed single-mode fiber-based polarization-sensitive optical coherence tomography (PS OCT) system was developed. With a polarization modulator, Stokes parameters of reflected flight for four input polarization states are measured as a function of depth. A phase modulator in the reference arm of a Michelson interferometer permits independent control of the axial scan rate and carrier frequency. In vivo PS OCT images of human skin are presented, showing subsurface structures that are not discernible in conventional OCT images. A phase retardation image in tissue is calculated based on the reflected Stokes parameters of the four input polarization states. (C) 2000 Optical Society of America.
引用
收藏
页码:1355 / 1357
页数:3
相关论文
共 11 条
  • [1] Imaging thermally damaged tissue by polarization sensitive optical coherence tomography
    de Boer, JF
    Srinivas, SM
    Malekafzali, A
    Chen, ZP
    Nelson, JS
    [J]. OPTICS EXPRESS, 1998, 3 (06): : 212 - 218
  • [2] Polarization effects in optical coherence tomography of various biological tissues
    de Boer, JF
    Srinivas, SM
    Park, BH
    Pham, TH
    Chen, ZP
    Milner, TE
    Nelson, JS
    [J]. IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 1999, 5 (04) : 1200 - 1204
  • [3] Determination of the depth-resolved Stokes parameters of light backscattered from turbid media by use of polarization-sensitive optical coherence tomography
    de Boer, JF
    Milner, TE
    Nelson, JS
    [J]. OPTICS LETTERS, 1999, 24 (05) : 300 - 302
  • [4] Two-dimensional birefringence imaging in biological tissue by polarization-sensitive optical coherence tomography
    deBoer, JF
    Milner, TE
    vanGemert, MJC
    Nelson, JS
    [J]. OPTICS LETTERS, 1997, 22 (12) : 934 - 936
  • [5] Birefringence characterization of biological tissue by use of optical coherence tomography
    Everett, MJ
    Schoenenberger, K
    Colston, BW
    Da Silva, LB
    [J]. OPTICS LETTERS, 1998, 23 (03) : 228 - 230
  • [6] POLARIZATION-SENSITIVE LOW-COHERENCE REFLECTOMETER FOR BIREFRINGENCE CHARACTERIZATION AND RANGING
    HEE, MR
    HUANG, D
    SWANSON, EA
    FUJIMOTO, JG
    [J]. JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS, 1992, 9 (06) : 903 - 908
  • [7] OPTICAL COHERENCE TOMOGRAPHY
    HUANG, D
    SWANSON, EA
    LIN, CP
    SCHUMAN, JS
    STINSON, WG
    CHANG, W
    HEE, MR
    FLOTTE, T
    GREGORY, K
    PULIAFITO, CA
    FUJIMOTO, JG
    [J]. SCIENCE, 1991, 254 (5035) : 1178 - 1181
  • [8] STATISTICAL TREATMENT OF POLARIZATION DISPERSION IN SINGLE-MODE FIBER
    POOLE, CD
    [J]. OPTICS LETTERS, 1988, 13 (08) : 687 - 689
  • [9] In vivo video rate optical coherence tomography
    Rollins, AM
    Kulkarni, MD
    Yazdanfar, S
    Ung-arunyawee, R
    Izatt, JA
    [J]. OPTICS EXPRESS, 1998, 3 (06): : 219 - 229
  • [10] High-speed phase- and group-delay scanning with a grating-based phase control delay line
    Tearney, GJ
    Bouma, BE
    Fujimoto, JG
    [J]. OPTICS LETTERS, 1997, 22 (23) : 1811 - 1813