AOD: the antioxidant protein database

被引：54

作者：

Feng, Pengmian ^{[1
]}

Ding, Hui ^{[2
]}

Lin, Hao ^{[2
]}

Chen, Wei ^{[3
,4
]}

机构：

[1] North China Univ Sci & Technol, Sch Publ Hlth, Hebei Prov Key Lab Occupat Hlth & Safety Coal Ind, Tangshan 063000, Peoples R China

[2] Univ Elect Sci & Technol China, Sch Life Sci & Technol, Ctr Informat Biol, Key Lab Neuroinformat,Minist Educ, Chengdu 610054, Sichuan, Peoples R China

[3] North China Univ Sci & Technol, Dept Phys, Sch Sci, Tangshan 063000, Peoples R China

[4] North China Univ Sci & Technol, Ctr Genom & Computat Biol, Tangshan 063000, Peoples R China

来源：

SCIENTIFIC REPORTS | 2017年 / 7卷

关键词：

GLUTATHIONE; DISEASE; CANCER;

D O I：

10.1038/s41598-017-08115-6

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An antioxidant is a molecule that can prevent free radicals from causing damages in organisms. The increasing studies on antioxidants calls for a specialized database that is not readily available yet. To this end, in the present study, the Antioxidant Database (AOD) was developed to help researchers understand and reveal the biological functions of antioxidant proteins. AOD is freely available at http://lin.uestc.edu.cn/AODdatabase/index.aspx. The current release of AOD consists of 710 antioxidant proteins. Information including taxonomy, source organism, subcellular location, gene ontology, catalytic activity and function of antioxidant proteins are all extracted from UniProtKB/Swiss-Prot and captured in AOD. In addition, two web-based tools for performing sequence similarity search and computationally identification of antioxidants were also integrated in AOD. We believe that AOD will greatly facilitate the researches on antioxidants.

引用

页数：4

共 21 条

[11] Coronary artery disease - free radical damage, antioxidant protection and the role of homocysteine [J].