Gender disparities in serum electrolytes levels after subarachnoid hemorrhage

被引:7
作者
Fukui, S [1 ]
Katoh, H [1 ]
Tsuzuki, N [1 ]
Ishihara, S [1 ]
Otani, N [1 ]
Uozumi, Y [1 ]
Ooigawa, H [1 ]
Toyooka, T [1 ]
Ohnuki, A [1 ]
Miyazawa, T [1 ]
Nawashiro, H [1 ]
Shima, K [1 ]
机构
[1] Natl Def Med Coll, Dept Neurosurg, Tokorozawa, Saitama 3598513, Japan
关键词
subarachnoid hemorrhage; gender disparity; electrolyte abnormality;
D O I
10.1016/j.jocn.2003.02.016
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We retrospectively studied 133 patients with subarachnoid hemorrhage (SAH) to assess whether there was any gender disparity in serum electrolytes levels throughout the clinical course. Serum concentrations of sodium and potassium were measured in all patients, while catecholamines or antidiuretic hormone were assessed in a number of cases. Female SAH-patients had lower potassium level (3.29 +/- 0.47 mEq/L) than did male patients (3.68 +/- 0.38) on the first day of SAH. This gender disparity continued to the beginning of the chronic phase and disappeared several months later. Mean serum sodium level was lower in the male group than in the female group throughout the clinical course. Mean serum levels of adrenaline and antidiuretic hormone were characterized by their prominent high value on the first day. Serum potassium levels were inversely related to serum levels of catecholamines, especially adrenaline, during the acute and subacute phases, particularly on the first day. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:606 / 609
页数:4
相关论文
共 22 条
[1]   SUBARACHNOID HEMORRHAGE - FREQUENCY AND SEVERITY OF CARDIAC-ARRHYTHMIAS - A SURVEY OF 70 CASES STUDIED IN THE ACUTE PHASE [J].
ANDREOLI, A ;
DIPASQUALE, G ;
PINELLI, G ;
GRAZI, P ;
TOGNETTI, F ;
TESTA, C .
STROKE, 1987, 18 (03) :558-564
[2]  
[Anonymous], ENDOCRINOLOGYAND MET
[3]   Secretion of brain natriuretic peptide in patients with aneurysmal subarachnoid haemorrhage [J].
Berendes, E ;
Walter, M ;
Cullen, P ;
Prien, T ;
VanAken, H ;
Horsthemke, J ;
Schulte, M ;
vonWild, K ;
Scherer, R .
LANCET, 1997, 349 (9047) :245-249
[4]   HYPOKALEMIA FROM BETA-2-RECEPTOR STIMULATION BY CIRCULATING EPINEPHRINE [J].
BROWN, MJ ;
BROWN, DC ;
MURPHY, MB .
NEW ENGLAND JOURNAL OF MEDICINE, 1983, 309 (23) :1414-1419
[5]   FEMALE PREPONDERANCE IN DIURETIC-ASSOCIATED HYPOKALEMIA - A RETROSPECTIVE STUDY IN 7 LONG-TERM CARE FACILITIES [J].
CLARK, BG ;
WHEATLEY, R ;
RAWLINGS, JL ;
VESTAL, RE .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1982, 30 (05) :316-321
[6]   Epinephrine-induced changes in serum potassium and cardiac repolarization and effects of pretreatment with propranolol and diltiazem [J].
Darbar, D ;
Smith, M ;
Morike, K ;
Roden, DM .
AMERICAN JOURNAL OF CARDIOLOGY, 1996, 77 (15) :1351-1355
[7]  
Di Pasquale G, 1998, J Neurosurg Sci, V42, P33
[8]   RELATION OF CEREBRAL VASOSPASM TO SUBARACHNOID HEMORRHAGE VISUALIZED BY COMPUTERIZED TOMOGRAPHIC SCANNING [J].
FISHER, CM ;
KISTLER, JP ;
DAVIS, JM .
NEUROSURGERY, 1980, 6 (01) :1-9
[9]   Female gender as a risk factor for hypokalemia and QT prolongation after subarachnoid hemorrhage [J].
Fukui, S ;
Otani, N ;
Katoh, H ;
Tsuzuki, N ;
Ishihara, S ;
Ohnuki, A ;
Miyazawa, T ;
Nawashiro, H ;
Shima, K .
NEUROLOGY, 2002, 59 (01) :134-136
[10]   Cerebral salt wasting syndrome: A review [J].
Harrigan, MR .
NEUROSURGERY, 1996, 38 (01) :152-160