Psychopharmacology of Attention-Deficit Hyperactivity Disorder: Effects and Side Effects

被引：40

作者：

Golmirzaei, Javad ^{[1
]}

Mahboobi, Hamidreza ^{[2
,3
]}

Yazdanparast, Maryam ^{[2
]}

Mushtaq, Gohar ^{[4
]}

Kamal, Mohammad A. ^{[5
,6
]}

Hamzei, Enayatollah ^{[7
]}

机构：

[1] Shahid Beheshti Univ Med Sci, Tehran, Iran

[2] Hormozgan Univ Med Sci, Infect & Trop Dis Res Ctr, Bandar Abbas, Iran

[3] PNU, Tehran, Iran

[4] King Abdulaziz Univ, Coll Sci, Dept Biochem, Jeddah 21589, Saudi Arabia

[5] King Abdulaziz Univ, King Fahd Med Res Ctr, POB 80216, Jeddah 21589, Saudi Arabia

[6] Enzymoics, 7Peterlee Pl, Hebersham, NSW 2770, Australia

[7] Hormozgan Univ Med Sci, Bandar Abbas, Hormozgan, Iran

来源：

CURRENT PHARMACEUTICAL DESIGN | 2016年 / 22卷 / 05期

关键词：

Attention-deficit hyperactivity disorder; Methylphenidate; Atomoxetine; Amphetamines; SELF-REPORT SCALE; LISDEXAMFETAMINE DIMESYLATE; ADULT ADHD; METHYLPHENIDATE TREATMENT; COLLEGE-STUDENTS; CONTROLLED-TRIAL; DOUBLE-BLIND; DRIVING PERFORMANCE; CHILDHOOD ADHD; SUBSTANCE USE;

D O I：

10.2174/1381612822666151124235816

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Attention-deficit hyperactivity disorder (ADHD) is a common psychiatric disorder in children which manifests with hyperactivity, impulsivity, and/or inattention. Several drugs are used in treatment of ADHD. Stimulants, atomoxetine, anti-depressants, and bupropion are common medications used in the treatment of ADHD. Stimulants are widely used as the first line treatment in children with ADHD. Their mechanism of action is the release of dopamine and norepinephrine in central nervous system. Methylphenidate is the most common stimulant used for the treatment of ADHD. Methylphenidate significantly reduces ADHD symptoms in children both at home and school and improves their social skills. Methylphenidate is safe in healthy children and has shown to have no cardiac side effects in these patients. Other medications include: Atomoxetine, Amphetamines, Clonidine, Melatonin, and anti-depressants. Effects, side effects, and mechanism of action these drugs have been discussed in this paper.

引用

页码：590 / 594

页数：5

共 66 条

[1] Changes in plasma Brain-derived neurotrophic factor (BDNF) levels induced by methylphenidate in children with Attention deficit-hyperactivity disorder (ADHD) [J].