Genetic Testing in Persons with Age-Related Macular Degeneration and the Use of the AREDS Supplements: To Test or Not to Test?

被引：39

作者：

Chew, Emily Y. ^{[1
]}

Klein, Michael L. ^{[2
]}

Clemons, Traci E. ^{[3
]}

Agron, Elvira ^{[1
]}

Abecasis, Goncalo R. ^{[4
]}

机构：

[1] NEI, Clin Trials Branch, Div Epidemiol & Clin Applicat, NIH, Bethesda, MD 20892 USA

[2] Oregon Hlth & Sci Univ, Casey Eye Inst, Portland, OR 97201 USA

[3] EMMES Corp, Rockville, MD USA

[4] Univ Michigan, Sch Publ Hlth, Dept Biostat, Ctr Stat Genet, Ann Arbor, MI 48109 USA

来源：

OPHTHALMOLOGY | 2015年 / 122卷 / 01期

关键词：

ZINC; CFH; ANTIOXIDANTS; GENOTYPES;

D O I：

10.1016/j.ophtha.2014.10.012

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

[No abstract available]

引用

页码：212 / 215

页数：5

共 5 条

[1] Treatment Response to Antioxidants and Zinc Based on CFH and ARMS2 Genetic Risk Allele Number in the Age-Related Eye Disease Study [J].

Awh, Carl C. ;

Hawken, Steven ;

Zanke, Brent W. .

OPHTHALMOLOGY, 2015, 122 (01) :162-169

[2] CFH and ARMS2 Genetic Polymorphisms Predict Response to Antioxidants and Zinc in Patients with Age-related Macular Degeneration [J].

Awh, Carl C. ;

Lane, Anne-Marie ;

Hawken, Steven ;

Zanke, Brent ;

Kim, Ivana K. .

OPHTHALMOLOGY, 2013, 120 (11) :2317-2323

[3] No Clinically Significant Association between CFH and ARMS2 Genotypes and Response to Nutritional Supplements AREDS Report Number 38 [J].

Chew, Emily Y. ;

Klein, Michael L. ;

Clemons, Traci E. ;

Agron, Elvira ;

Ratnapriya, Rinki ;

Edwards, Albert O. ;

Fritsche, Lars G. ;

Swaroop, Anand ;

Abecasis, Goncalo R. .

OPHTHALMOLOGY, 2014, 121 (11) :2173-2180

[4] A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss - AREDS Report No. 8 [J].

Kassoff, A ;

Kassoff, J ;

Buehler, J ;

Eglow, M ;

Kaufman, F ;

Mehu, M ;

Kieval, S ;

Mairs, M ;

Graig, B ;

Quattrocchi, A ;

Jones, D ;

Locatelli, J ;

Ruby, A ;

Capone, A ;

Garretson, B ;

Hassan, T ;

Trese, MT ;

Williams, GA ;

Regan, V ;

Manatrey, P ;

Streasick, P ;

Szydlowski, L ;

McIver, F ;

Bridges, C ;

Stanley, C ;

Cumming, K ;

Lewis, B ;

Zajechowski, M ;

Margherio, RR ;

Cox, MS ;

Camille, J ;

Falk, R ;

Siedlak, P ;

Neubert, C ;

Klein, ML ;

Stout, JT ;

O'Malley, A ;

Lauer, AK ;

Robertson, JE ;

Wilson, DJ ;

Beardsley, C ;

Anderson, H ;

Wallace, P ;

Smith, G ;

Howard, S ;

Dreyer, RF ;

Ma, C ;

Chenoweth, RG ;

Zilis, JD ;

Johnson, M .

ARCHIVES OF OPHTHALMOLOGY, 2001, 119 (10) :1417-1436

[5] CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration [J].

Klein, Michael L. ;

Francis, Peter J. ;

Rosner, Bernard ;

Reynolds, Robyn ;

Hamon, Sara C. ;

Schultz, Dennis W. ;

Ott, Jurg ;

Seddon, Johanna M. .

OPHTHALMOLOGY, 2008, 115 (06) :1019-1025

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