Nitriles in organic synthesis: Synthesis of some new 2-heterocyclic benzothiazole derivatives

被引：10

作者：

Fadda, A. A.

Zaki, M. E. A.

Samir, K. ^{[1
]}

Amer, F. A.

机构：

[1] Mansoura Univ, Fac Sci, Dept Chem, Mansoura, Egypt

[2] Natl Res Ctr, Photochem Dept, Cairo, Egypt

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 2007年 / 182卷 / 08期

关键词：

cyanomethylbenzothiazole; benzothiazole; pyrazole;

D O I：

10.1080/10426500701323432

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

2-Cyanomethylbenzothiazole (1) was utilized for the synthesis of several new 2-heteryl benzothiazole derivatives as pyrazolyl, thienyl, pyridyl, benzoimidazolyl, and benzothiazolyl derivatives.

引用

页码：1845 / 1856

页数：12

共 10 条

[1] SYNTHESIS OF 2-[BENZAZOLYL-(2)]-3,3-BIS-(ALKYLTHIO)-ACRYLNITRILES AND THEIR REACTIONS WITH N-NUCLEOPHILES [J].

AUGUSTIN, M ;

DOLLING, W .

JOURNAL FUR PRAKTISCHE CHEMIE, 1982, 324 (01) :3-11

[2]

Bharatham N, 2006, B KOREAN CHEM SOC, V27, P266

[3]

CHUIGUK VA, 1975, KHIM GETEROTSIKL+, P530

[4] Revised synthesis of some new 2-heterocyclic benzothiazolyl derivatives of biological interest [J].

Fadda, AA ;

Amer, FA ;

Zaki, MEA ;

Samir, KH .

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 1999, 155 :59-66

[5] Synthesis and biological activity of [[(heterocycloamino)alkoxy] benzyl]-2,4-thiazolidinediones as PPARγ agonists [J].

Jeon, R ;

Kim, YJ ;

Cheon, Y ;

Ryu, JH .

ARCHIVES OF PHARMACAL RESEARCH, 2006, 29 (05) :394-399

[6]

KUZMENKO VV, 1981, KHIM GETEROTSIKL+, P1497

[7] Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors:: Discovery of a highly potent in vivo inhibitor and its action mechanism [J].

Pietrancosta, Nicolas ;

Moumen, Anice ;

Dono, Rosanna ;

Lingor, Paul ;

Planchamp, Veronique ;

Lamballe, Fabienne ;

Baehr, Mathias ;

Kraus, Jean-Louis ;

Maina, Flavio .

JOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (12) :3645-3652

[8]

TAKESHIMA T, 1970, J ORG CHEM, V35, P7

[9] Nitriles in organic synthesis: A convenient route to some heterocycles incorporating a benzothiazole moiety [J].

Zaki, M. E. A. ;

Fadda, A. A. ;

Samir, K. ;

Amer, F. A. .

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, 2006, 181 (08) :1815-1823

[10]

ZAKI MEA, 2003, CHEM HETEROCYCLIC CO, V39, P1413

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