Exercise-induced acute renal failure in a patient with renal hypouricemia

被引：13
|
作者：
Watanabe, T [1 ]
Abe, T [1 ]
Oda, Y [1 ]
机构：
[1] Niigata City Gen Hosp, Dept Pediat, Niigata 9508739, Japan
来源：
PEDIATRIC NEPHROLOGY | 2000年 / 14卷 / 8-9期
关键词：
renal hypouricemia; acute renal failure; urate transport;
D O I：
10.1007/s004679900233
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
We describe a case of exercise-induced acute renal failure (ARF) in a patient with hypouricernia. Following recovery from ARE the patient's serum urate concentration was 0.6-0.9 mg/dl, and the ratio of urate clearance to creatinine clearance (C-ua/C-Cr) was 31.9%-56.6%. There was no change in the C-ua/C-Cr following the administration of pyrazinamide or probenecid, suggesting defects of tubular urate/anion exchangers. Because the renal biopsy revealed acute tubular necrosis without uric acid crystals, the ARF of this patient might be due to oxygen free radicals resulting from exercise stress and hypouricemia.
引用
收藏
页码：851 / 852
页数：2
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