Expressed interleukin-23 in tumors induces systemic immunity and soluble IL-12P40 molecules inhibit interleukin-23-mediated antitumor responses

被引:0
|
作者
Tagawa, M [1 ]
Shimozato, O [1 ]
Wang, YQ [1 ]
Ugai, S [1 ]
Sakiyama, S [1 ]
机构
[1] Childrens Canc Res Inst, Div Pathol, Chuo Ku, Chiba 2608717, Japan
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
P27
引用
收藏
页码:856 / 856
页数:1
相关论文
共 32 条
  • [1] The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12
    Lupardus, Patrick J.
    Garcia, K. Christopher
    JOURNAL OF MOLECULAR BIOLOGY, 2008, 382 (04) : 931 - 941
  • [2] Roles of the novel interleukin-12-associated cytokine, interleukin-23, in the regulation of T-cell-mediated immunity
    Matsui, Masanori
    HEPATOLOGY RESEARCH, 2007, 37 : S310 - S318
  • [3] The role of endogenous interleukin-12 responses in antitumor effects of IL-23
    Kaneda, Hide
    Sato, Marimo
    Tahara, Hideaki
    CANCER RESEARCH, 2006, 66 (08)
  • [4] Nocardia farcinica Activates Human Dendritic Cells and Induces Secretion of Interleukin-23 (IL-23) Rather than IL-12p70
    Eisenblaetter, Martin
    Buchal, Ariane
    Gayum, Hermine
    Jasny, Edith
    Viveros, Pablo Renner
    Ulrichs, Timo
    Schneider, Thomas
    Schumann, Ralf R.
    Zweigner, Janine
    Ignatius, Ralf
    INFECTION AND IMMUNITY, 2012, 80 (12) : 4195 - 4202
  • [5] Interleukin-23 restores immunity to Mycobacterium tuberculosis infection in IL-12p40-deficient mice and is not required for the development of IL-17-secreting T cell responses
    Wozniak, Teresa M.
    Ryan, Anthony A.
    Britton, Warwick J.
    JOURNAL OF IMMUNOLOGY, 2006, 177 (12): : 8684 - 8692
  • [6] Anti-p40 Antibodies Ustekinumab and Briakinumab: Blockade of Interleukin-12 and Interleukin-23 in the Treatment of Psoriasis
    Gandhi, Mona
    Alwawi, Eihab
    Gordon, Kenneth B.
    SEMINARS IN CUTANEOUS MEDICINE AND SURGERY, 2010, 29 (01) : 48 - 52
  • [7] Ciclosporin A inhibits production of interleukin-12/23p40 and interleukin-23 by the human monocyte cell line, THP-1
    Kamata, M.
    Tada, Y.
    Tatsuta, A.
    Kawashima, T.
    Shibata, S.
    Mitsui, H.
    Asano, Y.
    Sugaya, M.
    Kadono, T.
    Kanda, N.
    Watanabe, S.
    Sato, S.
    CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2013, 38 (05) : 545 - 548
  • [8] The expression of interleukin-23 (p19/p40) and interleukin-12 (p35/p40) in psoriasis skin
    Chen X.
    Tan Z.
    Yue Q.
    Liu H.
    Liu Z.
    Li J.
    Journal of Huazhong University of Science and Technology, 2006, 26 (6): : 750 - 752
  • [9] Interleukin-23 p19 and Interleukin-12 p40, Head-to-Head, against Gut Inflammation
    Abraham, Clara
    NEW ENGLAND JOURNAL OF MEDICINE, 2024, 391 (03): : 275 - 277
  • [10] Dataset on characterization of recombinant interleukin-23 alpha, IL-12p40 and IL-23 complex protein, which activates JAK-STAT signaling pathway in chicken cell lines using immunocytochemical staining
    Anh Duc Truong
    Cong Thanh Hoang
    Hong, Yeojin
    Lee, Janggeun
    Lee, Kyungbaek
    Lillehoj, Hyun S.
    Hong, Yeong Ho
    DATA IN BRIEF, 2018, 16 : 799 - 805