A global measure of sickness behaviour: Development of the Sickness Questionnaire

被引:60
作者
Andreasson, Anna [1 ,2 ]
Wicksell, Rikard K. [1 ,3 ]
Lodin, Karin [1 ]
Karshikoff, Bianka [1 ,2 ]
Axelsson, John [1 ,2 ]
Lekander, Mats [1 ,2 ]
机构
[1] Karolinska Inst, Stockholm, Sweden
[2] Stockholm Univ, Stockholm, Sweden
[3] Karolinska Univ Hosp, Solna, Sweden
基金
瑞典研究理事会;
关键词
endotoxin; sickness behaviour; Sickness Questionnaire; sickness response; validation; SELF-RATED HEALTH; BRAIN COMMUNICATION; PSYCHOSOCIAL STRESS; SAMPLE-SIZE; INFLAMMATION; PAIN; CYTOKINES; CINGULATE; SYMPTOMS;
D O I
10.1177/1359105316659917
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Symptoms after inflammatory activation, so-called sickness behaviour, overlap with trans-diagnostic complaints. As no self-report questionnaire to assess sickness behaviour exists, we aimed to develop such an instrument, the Sickness Questionnaire. Items responsive to experimentally induced inflammatory activation (randomized double-blind study endotoxin (0.6ng/kg) versus placebo, n=52) were selected and the statistical properties were examined in 172 primary care patients. A principal component analysis indicated a one-factor solution (Cronbach's alpha=.86). This 10-item scale correlated with depression (=.41, p<.001), anxiety (=.36, p<.001), self-rated health (=.28, p<.001) and a single item of feeling sick (=.55, p<.001). The results support the adequacy of Sickness Questionnaire as a brief assessment instrument of perceived sickness behaviour.
引用
收藏
页码:1452 / 1463
页数:12
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