3-Hydroxy fatty acids found in capsules of Cryptococcus neoformans

被引：19
作者：
Sebolai, Olihile M.
Pohl, Carolina H.
Botes, Piet J.
Strauss, Catharina J.
Van Wyk, Pieter W. J.
Botha, Alfred
Kock, Johan L. F.
机构：
[1] Univ Free State, Dept Microbial Biochem & Food Biotechnol, Ind Biotechnol, Bloemfontein, South Africa
[2] Univ Stellenbosch, Dept Microbiol, ZA-7600 Stellenbosch, South Africa
[3] Univ Free State, Ctr Confocal & Electron Microscopy, Bloemfontein, South Africa
来源：
CANADIAN JOURNAL OF MICROBIOLOGY | 2007年 / 53卷 / 06期
关键词：
capsule; Cryptococcus neoformans; 3-hydroxy fatty acid; protuberances;
D O I：
10.1139/W07-045
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Using immunofluorescence confocal laser scanning microscopy, immunogold transmission electron microscopy and gas chromatography - mass spectrometry, we demonstrated the presence of 3-hydroxy fatty acids in Cryptococcus neoformans. Our results suggest that these oxylipins accumulate in capsules where they are released as hydrophobic droplets through tubular protuberances into the surrounding medium.
引用
收藏
页码：809 / 812
页数：4
相关论文
共 22 条
  • [11] Nigam S, 1999, ADV EXP MED BIOL, V469, P663
  • [12] Production of eicosanoids and other oxylipins by pathogenic eukaryotic microbes
    Noverr, MC
    Erb-Downward, JR
    Huffnagle, GB
    [J]. CLINICAL MICROBIOLOGY REVIEWS, 2003, 16 (03) : 517 - +
  • [13] Of mice and men, revisited:: New insights into an ancient molecule from studies of complement activation by Cryptococcus neoformans
    Pirofski, Liise-Anne
    [J]. INFECTION AND IMMUNITY, 2006, 74 (06) : 3079 - 3084
  • [14] CRYPTOCOCCAL MENINGITIS AND AIDS
    POWDERLY, WG
    [J]. CLINICAL INFECTIOUS DISEASES, 1993, 17 (05) : 837 - 842
  • [15] BACTERIAL, ENDOTOXIN - MOLECULAR RELATIONSHIPS OF STRUCTURE TO ACTIVITY AND FUNCTION
    RIETSCHEL, ET
    KIRIKAE, T
    SCHADE, FU
    MAMAT, U
    SCHMIDT, G
    LOPPNOW, H
    ULMER, AJ
    ZAHRINGER, U
    SEYDEL, U
    DIPADOVA, F
    SCHREIER, M
    BRADE, H
    [J]. FASEB JOURNAL, 1994, 8 (02) : 217 - 225
  • [16] Rodrigues M. L., 2007, CELL, V6, P48
  • [17] The presence of 3-hydroxy oxylipins on the ascospore surfaces of some species representing Saccharomycopsis Schionning
    Sebolai, OM
    Kock, JLF
    Pohl, CH
    Botes, PJ
    Strauss, CJ
    Van Wyk, PWJ
    Nigam, S
    [J]. CANADIAN JOURNAL OF MICROBIOLOGY, 2005, 51 (07) : 605 - 612
  • [18] Antifungal 3-hydroxy fatty acids from Lactobacillus plantarum MiLAB 14
    Sjögren, J
    Magnusson, J
    Broberg, A
    Schnürer, J
    Kenne, L
    [J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2003, 69 (12) : 7554 - 7557
  • [19] Bioactive oxylipins in Saccharomyces cerevisiae
    Strauss, CJ
    Kock, JLF
    van Wyk, PWJ
    Lodolo, EJ
    Pohl, CH
    Botes, PJ
    [J]. JOURNAL OF THE INSTITUTE OF BREWING, 2005, 111 (03) : 304 - 308
  • [20] Ascospore release from bottle-shaped asci in Dipodascus albidus
    van Heerden, A
    Kock, JLF
    Botes, PJ
    Pohl, CH
    Strauss, CJ
    van Wyk, PWJ
    Nigam, S
    [J]. FEMS YEAST RESEARCH, 2005, 5 (12) : 1185 - 1190
123