3-Hydroxy fatty acids found in capsules of Cryptococcus neoformans

被引:19
作者
Sebolai, Olihile M.
Pohl, Carolina H.
Botes, Piet J.
Strauss, Catharina J.
Van Wyk, Pieter W. J.
Botha, Alfred
Kock, Johan L. F.
机构
[1] Univ Free State, Dept Microbial Biochem & Food Biotechnol, Ind Biotechnol, Bloemfontein, South Africa
[2] Univ Stellenbosch, Dept Microbiol, ZA-7600 Stellenbosch, South Africa
[3] Univ Free State, Ctr Confocal & Electron Microscopy, Bloemfontein, South Africa
关键词
capsule; Cryptococcus neoformans; 3-hydroxy fatty acid; protuberances;
D O I
10.1139/W07-045
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Using immunofluorescence confocal laser scanning microscopy, immunogold transmission electron microscopy and gas chromatography - mass spectrometry, we demonstrated the presence of 3-hydroxy fatty acids in Cryptococcus neoformans. Our results suggest that these oxylipins accumulate in capsules where they are released as hydrophobic droplets through tubular protuberances into the surrounding medium.
引用
收藏
页码:809 / 812
页数:4
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