N,N′-Mono substituted acyclic thioureas: efficient ligands for the palladium catalyzed Heck reaction of deactivated aryl bromides

被引：9

作者：

Keesara, Srinivas ^{[1
]}

Parvathaneni, Saiprathima ^{[1
]}

Mandapati, Mohan Rao ^{[1
]}

机构：

[1] Indian Inst Chem Technol, I&PC Div, Hyderabad 500607, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 50期

关键词：

Thiourea; Heck reaction; Phosphine free; Palladium; N-HETEROCYCLIC CARBENES; CROSS-COUPLING REACTION; SUZUKI REACTIONS; COMPLEXES; PD; PD(II); ACID;

D O I：

10.1016/j.tetlet.2014.09.053

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of N,N'-mono substituted acyclic thiourea ligands are found to be highly active phosphine-free catalysts for palladium catalyzed Heck reaction of aryl iodides and bromides with olefins. We have achieved high turnover numbers for aryl iodides with olefins (TONS up to 970,000 for the reaction of iodobenzene with styrene). (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：6769 / 6772

页数：4

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