Standardized uptake values of normal organs on 18F-fluorodeoxyglucose positron emission tomography and computed tomography imaging

被引:54
作者
Zincirkeser, S.
Sahin, E.
Halac, M.
Sager, S.
机构
[1] Gaziantep Univ, Nucl Med & Pet Ctr, Sch Med, TR-27310 Gaziantep, Turkey
[2] Istanbul Univ, Nucl Med & Pet Ctr, Cerrahpasa Med Sch, Istanbul, Turkey
关键词
cancer; inflammation; positron emission tomography (PET); computed tomography (CT); fluorodeoxyglucose (FDG); normal organs;
D O I
10.1177/147323000703500207
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Standardized uptake values (SUVs) of normal organs were evaluated by F-18-fluorodeoxyglucose (18F-FDG) positron emission tomography and computed tomography (PET-CT) scanning. Seventy patients (38 men and 32 women) with no non-physiological 18F-FDG uptake participated in the study. All patients fasted for at least 4 h before PET-CT imaging and their fasting blood glucose levels were within the normal range. Image acquisition was performed after intravenous administration of 18F-FDG and images were obtained from the vertex to the upper thigh region. The SUVs of various organs were determined from the transverse views. The uptake of 18F-FDG was highest in the cerebrum, cerebellum, myocardium, tonsils, liver and spleen in both sexes. Having knowledge of the physiological uptake of 18F-FDG and normal organ SUVs is required for the correct interpretation of whole-body 18F-FDG-PET-CT studies.
引用
收藏
页码:231 / 236
页数:6
相关论文
共 19 条
[1]   Fluorine-18 fluorodeoxyglucose splenic uptake from extramedullary hematopoiesis after granulocyte colony-stimulating factor stimulation [J].
Abdel-Dayem, HM ;
Rosen, G ;
El-Zeftawy, H ;
Naddaf, S ;
Kumar, M ;
Atay, S ;
Cacavio, A .
CLINICAL NUCLEAR MEDICINE, 1999, 24 (05) :319-322
[2]   Metabolic characterization of breast tumors with positron emission tomography using F-18 fluorodeoxyglucose [J].
Avril, N ;
Dose, J ;
Janicke, F ;
Bense, S ;
Ziegler, S ;
Laubenbacher, C ;
Romer, W ;
Pache, H ;
Herz, M ;
Allgayer, B ;
Nathrath, W ;
Graeff, H ;
Schwaiger, M .
JOURNAL OF CLINICAL ONCOLOGY, 1996, 14 (06) :1848-1857
[3]   Positron emission tomography and PET CT of the head and neck: FDG uptake in normal anatomy, in benign lesions, and in changes resulting from treatment [J].
Goerres, GW ;
von Schulthess, GK ;
Hany, TF .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2002, 179 (05) :1337-1343
[4]   PET diagnostic accuracy: Improvement with in-line PET-CT system: Initial results [J].
Hany, TF ;
Steinert, HC ;
Goerres, GW ;
Buck, A ;
von Schulthess, GK .
RADIOLOGY, 2002, 225 (02) :575-581
[5]  
Huang SC, 2000, NUCL MED BIOL, V27, P643
[6]  
Kamel EM, 2004, J NUCL MED, V45, P1804
[7]   Physiological FDG uptake in the palatine tonsils [J].
Kawabe, J ;
Okamura, T ;
Shakudo, M ;
Koyama, K ;
Sakamoto, H ;
Ohachi, Y ;
Higashiyama, S ;
Inoue, Y ;
Yamada, R ;
Ochi, H .
ANNALS OF NUCLEAR MEDICINE, 2001, 15 (03) :297-300
[8]  
KNUUTI MJ, 1993, J NUCL MED, V34, P2068
[9]  
KNUUTI MJ, 1992, J NUCL MED, V33, P1255
[10]   Prospective investigation of positron emission tomography in lung nodules [J].
Lowe, VJ ;
Fletcher, JW ;
Gobar, L ;
Lawson, M ;
Kirchner, P ;
Valk, P ;
Karis, J ;
Hubner, K ;
Delbeke, D ;
Heiberg, EV ;
Patz, EF ;
Coleman, RE .
JOURNAL OF CLINICAL ONCOLOGY, 1998, 16 (03) :1075-1084