International Consensus Guidelines on the Management of Cytomegalovirus in Solid Organ Transplantation

被引:442
作者
Kotton, Camille N. [1 ]
Kumar, Deepali
Caliendo, Angela M. [2 ]
Asberg, Anders [3 ]
Chou, Sunwen [4 ]
Snydman, David R. [5 ,6 ]
Allen, Upton [7 ]
Humar, Atul
机构
[1] Massachusetts Gen Hosp, Div Infect Dis, Boston, MA 02114 USA
[2] Emory Univ Hosp, Sch Med, Dept Pathol & Lab Med, Atlanta, GA 30322 USA
[3] Univ Oslo, Sch Pharm, Dept Pharmaceut Biosci, Oslo, Norway
[4] Oregon Hlth & Sci Univ, Div Infect Dis L457, Portland, OR 97201 USA
[5] Tufts Univ, Sch Med, Div Geog Med & Infect Dis, Boston, MA 02111 USA
[6] Tufts Univ, Sch Med, Tufts Med Ctr, Boston, MA 02111 USA
[7] Univ Toronto, Hosp Sick Children, Dept Pediat, Div Infect Dis, Toronto, ON M5G 1X8, Canada
关键词
Cytomegalovirus; Prophylaxis; Resistance; Ganciclovir; Valganciclovir; GANCICLOVIR-RESISTANT CYTOMEGALOVIRUS; T-CELL RESPONSES; BRONCHOALVEOLAR LAVAGE FLUID; GUIDING PREEMPTIVE THERAPY; AMPLICOR CMV MONITOR; LIVER-TRANSPLANT; RENAL-TRANSPLANT; DRUG-RESISTANCE; INTRAVENOUS GANCICLOVIR; VALGANCICLOVIR THERAPY;
D O I
10.1097/TP.0b013e3181cee42f
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Cytomegalovirus (CMV) remains one of the most common infections after solid organ transplantation, resulting in significant morbidity, graft loss, and occasional mortality. Management of CMV varies considerably among transplant centers. A panel of experts on CMV and solid organ transplant was convened by The Infectious Diseases Section of The Transplantation Society to develop evidence and expert opinion-based consensus guidelines on CMV management including diagnostics, immunology, prevention, treatment, drug resistance, and pediatric issues.
引用
收藏
页码:779 / 795
页数:17
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