Critical Limb Ischemia

被引：29

作者：

Elsayed, Sarah ^{[1
]}

Clavijo, Leonardo C. ^{[2
]}

机构：

[1] Univ So Calif, Div Cardiovasc Med, Los Angeles, CA 90033 USA

[2] Univ So Calif, Intervent Cardiol Fellowship Program, Div Cardiovasc Med, Los Angeles, CA 90033 USA

来源：

CARDIOLOGY CLINICS | 2015年 / 33卷 / 01期

关键词：

Critical limb ischemia; Diagnosis; Management; Endovascular; Guidelines; Review; PERIPHERAL ARTERIAL-DISEASE; ASSOCIATION TASK-FORCE; LEG BASIL TRIAL; LOWER-EXTREMITY; MANAGEMENT; BYPASS; SURGERY; ANGIOPLASTY; CLOPIDOGREL; GUIDELINE;

D O I：

10.1016/j.ccl.2014.09.008

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Critical limb ischemia (CLI), the most advanced form of peripheral artery disease (PAD), carries grave implications with regard to morbidity and mortality. Within 1 year of CLI diagnosis, 40% to 50% of diabetics will experience an amputation, and 20% to 25% will die. Management is optimally directed at increasing blood flow to the affected extremity to relieve rest pain, heal ischemic ulcerations, avoid limb loss, and prevent cardiovascular events. This management is achieved by guideline-directed medical therapy and risk factor modification, whereas the mainstay of therapy remains revascularization by endovascular or surgical means for patients who are deemed potential candidates.

引用

页码：37 / +

页数：12

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