Antifungal amides from Piper hispidum and Piper tuberculatum

被引：151

作者：

Navickiene, HMD

Alécio, AC

Kato, MJ

Bolzani, VD

Young, MCM

Cavalheiro, AJ

Furlan, M

机构：

[1] Univ Estadual Paulista, Inst Quim, BR-14800900 Araraquara, SP, Brazil

[2] Univ Sao Paulo, Inst Quim, BR-05599970 Sao Paulo, Brazil

[3] Inst Bot, Secao Fisiol & Bioquim Plantas, BR-10051 Sao Paulo, Brazil

来源：

PHYTOCHEMISTRY | 2000年 / 55卷 / 06期

基金：

巴西圣保罗研究基金会;

关键词：

Piper hispidum; Piper tuberculatum; Piperaceae; amides; antifungal activity;

D O I：

10.1016/S0031-9422(00)00226-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Piper hispidum and Piper tuberculatum accumulate amides bearing isobutyl, pyrrolidine, dihydropyridone and piperidine moieties. The isolation and characterization of several representatives including two hitherto unreported amides were performed by chromatographic techniques and by analysis of spectroscopic data. The antifungal activity of each amide was determined by direct bioautography against Cladosporium sphaerospermum. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：621 / 626

页数：6

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