The therapeutic workplace to promote treatment engagement and drug abstinence in out-of-treatment injection drug users: A randomized controlled trial

被引:23
|
作者
Holtyn, August F. [1 ]
Koffarnus, Mikhail N. [2 ]
DeFulio, Anthony [1 ]
Sigurdsson, Sigurdur O. [1 ,3 ]
Strain, Eric C. [1 ]
Schwartz, Robert P. [4 ]
Leoutsakos, Jeannie-Marie S. [1 ]
Silverman, Kenneth [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, Baltimore, MD 21224 USA
[2] Virginia Tech, Carillon Res Inst, Blacksburg, VA 24061 USA
[3] Florida Inst Technol, Melbourne, FL 32901 USA
[4] Friends Res Inst, Baltimore, MD 21201 USA
关键词
Methadone; Contingency management; Financial incentives; Cocaine; Opiate; Employment; Injection drug use; Out-of-treatment injection drug user; EMPLOYMENT-BASED REINFORCEMENT; IMMUNODEFICIENCY-VIRUS SEROCONVERSION; METHADONE-MAINTENANCE TREATMENT; OPIOID-DEPENDENT ADULTS; 33-YEAR FOLLOW-UP; COCAINE ABSTINENCE; TREATMENT ENROLLMENT; CASE-MANAGEMENT; ABUSE; RISK;
D O I
10.1016/j.ypmed.2014.02.021
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objective: Determine if employment-based reinforcement can increase methadone treatment engagement and drug abstinence in out-of-treatment injection drug users. Method: This study was conducted from 2008 to 2012 in a therapeutic workplace in Baltimore, MD. After a 4-week induction, participants (N = 98) could work and earn pay for 26 weeks and were randomly assigned to Work Reinforcement, Methadone & Work Reinforcement, and Abstinence, Methadone & Work Reinforcement conditions. Work Reinforcement participants had to work to earn pay. Methadone & Work Reinforcement and Abstinence, Methadone, & Work Reinforcement participants had to enroll in methadone treatment to work and maximize pay. Abstinence, Methadone, & Work Reinforcement participants had to provide opiate- and cocaine-negative urine samples to maximize pay. Results: Most participants (92%) enrolled in methadone treatment during induction. Drug abstinence increased as a graded function of the addition of the methadone and abstinence contingencies. Abstinence, Methadone & Work Reinforcement participants provided significantly more urine samples negative for opiates (75% versus 54%) and cocaine (57% versus 32%) than Work Reinforcement participants. Methadone & Work Reinforcement participants provided significantly more cocaine-negative samples than Work Reinforcement participants (55% versus 32%). Conclusion: The therapeutic workplace can promote drug abstinence in out-of-treatment injection drug users. (C) 2014 Elsevier Inc. All rights reserved.
引用
收藏
页码:62 / 70
页数:9
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