Potential Neurologic Manifestations of COVID-19

被引：63

作者：

Nordvig, Anna S. ^{[1
,2
]}

Fong, Kathryn T. ^{[1
,2
]}

Willey, Joshua Z. ^{[1
,2
]}

Thakur, Kiran T. ^{[1
,2
]}

Boehme, Amelia K. ^{[1
,2
,3
]}

Vargas, Wendy S. ^{[1
,2
]}

Smith, Craig J. ^{[4
,5
]}

Elkind, Mitchell S., V ^{[1
,2
,3
]}

机构：

[1] Columbia Univ, Vagelos Coll Phys & Surg, Dept Neurol, New York, NY 10027 USA

[2] New York Presbyterian Hosp, New York, NY 10032 USA

[3] Columbia Univ, Mailman Sch Publ Hlth, Dept Epidemiol, New York, NY USA

[4] Univ Manchester, Lydia Becker Inst Immunol & Inflammat, Div Cardiovasc Sci, Manchester, Lancs, England

[5] Salford Royal NHS Fdn Trust, Manchester Acad Hlth Sci Ctr, Ctr Clin Neurosci, Salford, Lancs, England

来源：

NEUROLOGY-CLINICAL PRACTICE | 2021年 / 11卷 / 02期

关键词：

RESPIRATORY SYNDROME CORONAVIRUS; CENTRAL-NERVOUS-SYSTEM; SARS; INFECTION; BRAIN; MICE; DISEASE;

D O I：

10.1212/CPJ.0000000000000897

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Purpose of Review Neurologic complications are increasingly recognized in the coronavirus disease 2019 (COVID-19) pandemic. COVID-19 is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This coronavirus is related to severe acute respiratory syndrome coronavirus (SARS-CoV) and other human coronavirus-related illnesses that are associated with neurologic symptoms. These symptoms raise the question of a neuroinvasive potential of SARS-CoV-2. Recent Findings Potential neurologic symptoms and syndromes of SARS-CoV-2 include headache, fatigue, dizziness, anosmia, ageusia, anorexia, myalgias, meningoencephalitis, hemorrhage, altered consciousness, Guillain-Barre syndrome, syncope, seizure, and stroke. In addition, we discuss neurologic effects of other coronaviruses, special considerations for management of neurologic patients, and possible long-term neurologic and public health sequelae. Summary As SARS-CoV-2 is projected to infect a large part of the world's population, understanding the potential neurologic implications of COVID-19 will help neurologists and others recognize and intervene in neurologic morbidity during and after the pandemic of 2020.

引用

页码：E135 / E146

页数：12

共 39 条

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