Knoevenagel condensation catalyzed by chemo-selective Ni-nanoparticles in neutral medium

被引:36
作者
Kumar, Ajeet [1 ]
Dewan, Manika [1 ]
Saxena, Amit [1 ]
De, Arnab
Mozumdar, Subho [1 ]
机构
[1] Univ Delhi, Dept Chem, Delhi 7, India
关键词
Knoevenagel condensation; Ni-nanoparticles; Neutral medium; Active methylene compounds; DIELS-ALDER REACTIONS; DERIVATIVES; EFFICIENT;
D O I
10.1016/j.catcom.2010.01.017
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Recyclable Ni-nanoparticles provides an efficient, economic and rapid method for catalyzing Knoevenagel condensation of aldehydes with an active methylene compound at room temperature. The method offers high yield preferably in case of aromatic aldehydes and proceed well in neutral medium. This method provides a wide range of substrate applicability and simple workup procedure. The products need no further purification and the process is environmentally benign. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:679 / 683
页数:5
相关论文
共 29 条
[21]  
TIETZE LF, 1992, SYNLETT, P281
[22]   INTERMOLECULAR AND INTRAMOLECULAR HETERO-DIELS-ALDER REACTIONS .31. SYNTHESIS OF D-HOMOESTRONE DERIVATIVES BY TANDEM KNOEVENAGEL HETERO-DIELS-ALDER REACTIONS FROM NATURAL ESTRONE [J].
TIETZE, LF ;
WOLFLING, J ;
SCHNEIDER, G .
CHEMISCHE BERICHTE, 1991, 124 (03) :591-594
[23]   Domino reactions in organic synthesis [J].
Tietze, LF .
CHEMICAL REVIEWS, 1996, 96 (01) :115-136
[24]   Calcite and fluorite as catalyst for the Knovenagel condensation of malononitrile and methyl cyanoacetate under solvent-free conditions [J].
Wada, S ;
Suzuki, H .
TETRAHEDRON LETTERS, 2003, 44 (02) :399-401
[25]   Unexpected formation of tetrasubstituted 2,3-dihydrofurans from the reactions of β-keto polyfluoroalkanesulfones with aldehydes [J].
Xing, CH ;
Zhu, SZ .
JOURNAL OF ORGANIC CHEMISTRY, 2004, 69 (19) :6486-6488
[26]   [Bmim]BF4 ionic liquid:: a novel reaction medium for the synthesis of β-amino alcohols [J].
Yadav, JS ;
Reddy, BVS ;
Basak, AK ;
Narsaiah, AV .
TETRAHEDRON LETTERS, 2003, 44 (05) :1047-1050
[27]   A novel, practical and green synthesis of Ag nanoparticles catalyst and its application in three-component coupling of aldehyde, alkyne, and amine [J].
Yan, Wenjin ;
Wang, Rui ;
Xu, Zhaoqing ;
Xu, Jiangke ;
Lin, Li ;
Shen, Zhiqiang ;
Zhou, Yifeng .
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2006, 255 (1-2) :81-85
[28]   Reactions of salicylaldehydes with alkyl cyanoacetates on the surface of solid catalysts:: syntheses of 4H-chromene derivatives [J].
Yu, NF ;
Aramini, JM ;
Germann, MW ;
Huang, ZW .
TETRAHEDRON LETTERS, 2000, 41 (36) :6993-6996
[29]   Synergistic enhancement effect of magnetic nanoparticles on anticancer drug accumulation in cancer cells [J].
Zhang, Renyun ;
Wang, Xuemei ;
Wu, Chunhui ;
Song, Min ;
Li, Jingyuan ;
Lv, Gang ;
Zhou, Jian ;
Chen, Chen ;
Dai, Yongyuan ;
Gao, Feng ;
Fu, Degang ;
Li, Xiaomao ;
Guan, Zhiqun ;
Chen, Boan .
NANOTECHNOLOGY, 2006, 17 (14) :3622-3626