Body dysmorphic disorder: a treatment synthesis and consensus on behalf of the International College of Obsessive-Compulsive Spectrum Disorders and the Obsessive Compulsive and Related Disorders Network of the European College of Neuropsychopharmacology

被引:24
作者
Castle, David [1 ,2 ]
Beilharz, Francesca [3 ]
Phillips, Katharine A. [4 ,5 ]
Brakoulias, Vlasios [6 ,7 ]
Drummond, Lynne M. [8 ]
Hollander, Eric [9 ]
Ioannidis, Konstantinos [10 ,11 ]
Pallanti, Stefano [9 ,12 ]
Chamberlain, Samuel R. [10 ,13 ,14 ,15 ]
Rossell, Susan L. [2 ,3 ]
Veale, David [16 ,17 ]
Wilhelm, Sabine [18 ]
Van Ameringen, Michael [19 ]
Dell'Osso, Bernardo [20 ]
Menchon, Jose M. [21 ]
Fineberg, Naomi A. [22 ,23 ]
机构
[1] Univ Melbourne, Dept Psychiat, Melbourne, Vic, Australia
[2] St Vincents Hosp, Melbourne, Vic, Australia
[3] Swinburne Univ, Ctr Mental Hlth, Melbourne, Vic, Australia
[4] Weill Cornell Med Coll, New York Presbyterian Hosp, New York, NY USA
[5] Weill Cornell Med Coll, Psychiat, New York, NY USA
[6] Western Sydney Univ, Sch Med, Sydney, NSW, Australia
[7] Western Sydney Local Hlth Dist, Sydney, NSW, Australia
[8] SW London & St Georges NHS Trust, Natl Serv OCD BDD, London, England
[9] Albert Einstein Coll Med, Bronx, NY USA
[10] Univ Cambridge, Dept Psychiat, Cambridge, Cambs, England
[11] Peterborough NHS Fdn Trust, Cambridge, England
[12] Ist Neurosci Univ Florence, Florence, Italy
[13] Univ Southampton, Dept Psychiat, Southampton, Hants, England
[14] Southern Hlth NHS Fdn Trust, Southampton, Hants, England
[15] Cambridgeshire & Peterborough NHS Fdn Trust, Dept Psychiat, Cambridge, England
[16] Kings Coll London, Dept Psychol, London, England
[17] South London & Maudsley NHS Fdn Trust, London, England
[18] Harvard Med Sch, Massachusetts Gen Hosp, Dept Psychiat, Cambridge, MA USA
[19] McMaster Univ, Dept Psychiat & Behav Neurosci, Hamilton, ON, Canada
[20] Univ Milan, Luigi Sacco Hosp, Dept Biomed & Clin Sci Luigi Sacco, Milan, Italy
[21] Univ Barcelona, Dept Psychiat, Cibersam, Bellvitge Univ Hosp IDIBELL, Barcelona, Spain
[22] Univ Hertfordshire, Dept Clin & Pharmaceut Sci, Hatfield, Herts, England
[23] Hertfordshire Partnership Univ NHS Fdn Trust, Hatfield, Herts, England
关键词
antipsychotics; body dysmorphic disorder; cognitive-behaviour therapy; obsessive-compulsive disorder; serotonin reuptake inhibitors; COGNITIVE-BEHAVIORAL THERAPY; NONPSYCHIATRIC MEDICAL-TREATMENT; SEROTONIN-REUPTAKE INHIBITORS; EMOTION RECOGNITION DEFICITS; OPEN-LABEL; PHARMACOLOGICAL-TREATMENTS; SCREENING QUESTIONNAIRE; OLANZAPINE AUGMENTATION; ANOREXIA-NERVOSA; CONTROLLED-TRIAL;
D O I
10.1097/YIC.0000000000000342
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Body dysmorphic disorder (BDD) is characterized by a preoccupation with a perceived appearance flaw or flaws that are not observable to others. BDD is associated with distress and impairment of functioning. Psychiatric comorbidities, including depression, social anxiety, and obsessive-compulsive disorder are common and impact treatment. Treatment should encompass psychoeducation, particularly addressing the dangers associated with cosmetic procedures, and may require high doses of selective serotonin reuptake inhibitors* (SSRI*) and protracted periods to establish full benefit. If there is an inadequate response to SSRIs, various adjunctive medications can be employed including atypical antipsychotics*, anxiolytics*, and the anticonvulsant levetiracetam*. However, large-scale randomized controlled trials are lacking and BDD is not an approved indication for these medications. Oxytocin* may have a potential role in treating BDD, but this requires further exploration. Cognitive-behavioural therapy has good evidence for efficacy for BDD, and on-line and telephone-assisted forms of therapy are showing promise. CBT for BDD should be customized to address such issues as mirror use, perturbations of gaze, and misinterpretation of others' emotions, as well as overvalued ideas about how others view the individual.
引用
收藏
页码:61 / 75
页数:15
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