Isogenic lines in fish - a critical review

被引：29

作者：

Franek, Roman ^{[1
]}

Baloch, Abdul Rasheed ^{[1
]}

Kaspar, Vojtech ^{[1
]}

Saito, Taiju ^{[1
,2
]}

Fujimoto, Takafumi ^{[3
]}

Arai, Katsutoshi ^{[3
]}

Psenicka, Martin ^{[1
]}

机构：

[1] Univ South Bohemia Ceske Budejovice, Res Inst Fish Culture & Hydrobiol, South Bohemian Res Ctr Aquaculture & Biodivers Hy, Fac Fisheries & Protect Waters, Vodnany, Czech Republic

[2] Ehime Univ, South Ehime Fisheries Res Ctr, Nishimura Stn, Ainan, Ehime, Japan

[3] Hokkaido Univ, Fac & Grad Sch Fisheries Sci, Hakodate, Hokkaido, Japan

来源：

REVIEWS IN AQUACULTURE | 2020年 / 12卷 / 03期

基金：

欧盟地平线“2020”;

关键词：

androgenesis; doubled haploid; gynogenesis; isogenic line; model fish species; standardization; CARP CYPRINUS-CARPIO; TROUT ONCORHYNCHUS-MYKISS; GYNOGENETIC RAINBOW-TROUT; ZEBRAFISH DANIO-RERIO; SALMON SALMO-SALAR; INBRED MOUSE STRAINS; COMMON CARP; JAPANESE FLOUNDER; ATLANTIC SALMON; PARALICHTHYS-OLIVACEUS;

D O I：

10.1111/raq.12389

中图分类号：

S9 [水产、渔业];

学科分类号：

0908 ;

摘要：

An isogenic line is a group of animals with an identical genotype, and its use is widely accepted for bioresearch standardization. Isogenic lines in fish can be generated within two generations via uniparental inheritance and can facilitate studies for which standardization and consistency are required. The availability and use of isogenic lines is limited, but isogenic lines in some fish species have been generated. Their power has been demonstrated in fields including human disease modelling, drug development, toxicology and also sequencing projects. The genetic basis of desired traits in aquaculture species can be identified using isogenic lines, which, in turn, will help to improve fish culture. This review summarized knowledge regarding the present status of isogenic lines in fish including approaches for their generation and verification, as well as challenges and potential applications for basic research and aquaculture.

引用

页码：1412 / 1434

页数：23

共 248 条

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