Synthesis of pyranoquinoline alkaloids via (4+2) cycloaddition reaction

被引：0
|
作者：
Suresh, T [1 ]
Dhanabal, T [1 ]
Kumar, RN [1 ]
Mohan, PS [1 ]
机构：
[1] Bharathiar Univ, Dept Chem, Coimbatore 641046, Tamil Nadu, India
来源：
HETEROCYCLIC COMMUNICATIONS | 2005年 / 11卷 / 01期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An easy route to synthesize pyranoquinoline based alkaloids like flindersine, haplamine, N-methylflindersine and its derivatives were performed from the respective 4-hydroxyquinolin-2(1H)-one, dimethyl acrylic acid and para formaldehyde through generation of O-quinone methide intermediates and subjecting (4+2) cycloaddition. Further, dihydro intermediates were oxidized by DDQ.
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页码：79 / 84
页数：6
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