Synthesis of Well-Defined Thermoresponsive Polyphosphoester Macroinitiators Using Organocatalysts

被引：110

作者：

Iwasaki, Yasuhiko ^{[1
]}

Yamaguchi, Etsuko ^{[1
]}

机构：

[1] Kansai Univ, Fac Chem Mat & Bioengn, Dept Chem & Mat Engn, Suita, Osaka 5648680, Japan

来源：

MACROMOLECULES | 2010年 / 43卷 / 06期

关键词：

RING-OPENING POLYMERIZATION; POLY(ALKYLENE PHOSPHATES); BIOMEDICAL APPLICATIONS; CYCLIC ESTERS; SIDE-CHAINS; POLYMERS; PHOSPHORYLCHOLINE; TRANSESTERIFICATION;

D O I：

10.1021/ma100242s

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A study was conducted to demonstrate the synthesis of well-defined polyphosphoesters with a narrow molecular weight distribution and a high molecular weight using organocatalysts. Block copolymers with 2-methacryloyloxyethylphosphorylcholine (MPC) were also synthesized by using poly(2-isopropoxy-2-oxo-1,3,2-dioxaphospholane) (PIPP) as a macroinitiator. PIPP was synthesized by ring-opening polymerization (ROP) using an organocatalyst as an initiator in the presence of of HEBB. A given amount of organocatalyst was introduced and polymerization was carried out at 0 °C. The mechanism of ROP with organocatalysts was characterized using 1H NMR by the researchers.

引用

页码：2664 / 2666

页数：3

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