Meniere's disease caused by CGRP - A new hypothesis explaining etiology and pathophysiology. Redirecting Meniere's syndrome to Meniere's disease

被引:10
|
作者
Hegemann, Stefan Carl Anton [1 ,2 ]
机构
[1] Balance Clin, Nueschelerstr, Zurich, Switzerland
[2] Zurich Univ, Fac Med, Ramistr, Zurich, Switzerland
来源
JOURNAL OF VESTIBULAR RESEARCH-EQUILIBRIUM & ORIENTATION | 2021年 / 31卷 / 04期
关键词
GENE-RELATED PEPTIDE; ENDOLYMPHATIC HYDROPS; BLOOD; MIGRAINE; LEAKAGE;
D O I
10.3233/VES-200716
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
This paper provides a new hypothetical explanation for the etiopathology and pathophysiology of Meniere's Disease (MD), which to date remain unexplained, or incompletely understood. The suggested hypothesis will explain the close connection of MD and Migraine, the coexistence of endolymphatic hydrops (ELH) and Meniere attacks and the signs of inflammation detected in the inner ears of MD patients. Although as yet unproven, the explanations provided appear highly plausible and could pave the way for the generation of the first animal model of MD - an invaluable asset for developing new treatment strategies. Furthermore, if proven correct, this hypothesis could redefine and also reset the actual name of Meniere's Syndrome to Meniere's Disease.
引用
收藏
页码:311 / 314
页数:4
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