The Characteristics of TCM Clinical Trials: A Systematic Review of ClinicalTrials.gov

被引：28

作者：

Chen, Junchao ^{[1
]}

Huang, Jihan ^{[1
]}

Li, Jordan V. ^{[2
]}

Lv, Yinghua ^{[1
]}

He, Yingchun ^{[1
]}

Zheng, Qingshan ^{[1
]}

机构：

[1] Shanghai Univ Tradit Chinese Med, Ctr Drug Clin Res, Shanghai 201203, Peoples R China

[2] Med Sci & Comp LLC, Rockville, MD 20852 USA

来源：

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | 2017年 / 2017卷

关键词：

HERBAL MEDICINES; STATEMENT; THERAPY; QIGONG;

D O I：

10.1155/2017/9461415

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Objective. The aim of this review is to characterize current status of global TCM clinical trials registered in ClinicalTrials.gov. Methods. We examined all the trials registered within ClinicalTrials.gov up to 25 September 2015, focusing on study interventions to identify TCM-related trials, and extracted 1,270 TCM trials from the data set. Results. Overall, 691 (54.4%) trials were acupuncture, and 454 (35.8%) trials were herbal medicines. Differences in TCM trial intervention types were also evident among the specific therapeutic areas. Among all trials, 55.7% that were small studies enrolled <100 subjects, and only 8.7% of completed studies had reported results of trials. As for the location, the United States was second to China in conducting the most TCM trials. Conclusion. This review is the first snapshot of the landscape of TCM clinical trials registered in ClinicalTrials.gov, providing the basis for treatment and prevention of diseases within TCM and offering useful information that will guide future research on TCM.

引用

页数：9

共 24 条

[1] Understanding randomised controlled trials [J].

Akobeng, AK .

ARCHIVES OF DISEASE IN CHILDHOOD, 2005, 90 (08) :840-844

[2] Compliance with Results Reporting at ClinicalTrials.gov [J].

Anderson, Monique L. ;

Chiswell, Karen ;

Peterson, Eric D. ;

Tasneem, Asba ;

Topping, James ;

Califf, Robert M. .

NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (11) :1031-1039

[3]

[Anonymous], 2016, International statistical classification of diseases and related health problems - 10th Version, DOI DOI 10/2016/EN

[4]

[Anonymous], 2015, PROT DAT EL DEF

[5] T'ai Chi and Qigong for Health: Patterns of Use in the United States [J].

Birdee, Gurjeet S. ;

Wayne, Peter M. ;

Davis, Roger B. ;

Phillips, Russell S. ;

Yeh, Gloria Y. .

JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE, 2009, 15 (09) :969-973

[6] SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials [J].

Chan, An-Wen ;

Tetzlaff, Jennifer M. ;

Altman, Douglas G. ;

Laupacis, Andreas ;

Gotzsche, Peter C. ;

Krleza-Jeric, Karmela ;

Hrobjartsson, Asbjorn ;

Mann, Howard ;

Dickersin, Kay ;

Berlin, Jesse A. ;

Dore, Caroline J. ;

Parulekar, Wendy R. ;

Summerskill, William S. M. ;

Groves, Trish ;

Schulz, Kenneth F. ;

Sox, Harold C. ;

Rockhold, Frank W. ;

Rennie, Drummond ;

Moher, David .

ANNALS OF INTERNAL MEDICINE, 2013, 158 (03) :200-+

[7]

Chen J.T., 2008, MOD CHIN MED, V10, P19

[8] Review: Drug therapy in Chinese traditional medicine [J].

Cheng, JT .

JOURNAL OF CLINICAL PHARMACOLOGY, 2000, 40 (05) :445-450

[9] Clinical trial registration - A statement from the International Committee of Medical Journal Editors [J].

DeAngelis, CD ;

Drazen, JM ;

Frizelle, FA ;

Haug, C ;

Hoey, J ;

Horton, R ;

Kotzin, S ;

Laine, C ;

Marusic, A ;

Overbeke, AJPM ;

Schroeder, TV ;

Sox, HC ;

Van der Weyden, MB .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (11) :1363-1364

[10]

Fu Jun-ying, 2008, Zhong Xi Yi Jie He Xue Bao, V6, P551, DOI 10.3736/jcim20080601

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