SF3•Et2O catalyzed intramolecular cyclization of diethyl 2-(dialkoxyphosphorylethyny1)-2-arylaminomalonates to 3-phosphonylated indoles

被引：18
作者：
Egorova, Anastasia V. [1 ]
Viktorov, Nikolai B. [1 ]
Starova, Galina L. [2 ]
Svintsitskaya, Nataly I. [1 ]
Garabadziu, Aleksandr V. [1 ]
Dogadina, Albina V. [1 ]
机构：
[1] Tech Univ, St Petersburg State Inst Technol, Moskovskii Pr 26, St Petersburg 190013, Russia
[2] St Petersburg State Univ, Univ Skii Pr 26, St Petersburg 198504, Russia
来源：
TETRAHEDRON LETTERS | 2017年 / 58卷 / 30期
基金：
俄罗斯基础研究基金会;
关键词：
Phosphorylated indoles; Phosphonylated indoles; Aminomalonates; Phosphonylated 2-arylaminomalonic esters; Decarboxylation; NUCLEOPHILIC-SUBSTITUTION; PHOSPHORYLATION; DERIVATIVES; IDX899;
D O I：
10.1016/j.tetlet.2017.06.062
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The boron trifluoride diethyl etherate catalyzed intramolecular cyclization of diethyl 2-(dialkoxyphosphorylethynyl)-2-arylaminomalonates afforded a series of novel 3-phosphonylated indoles, diethyl 2[3-(dialkoxyphosphoryl)-1H-indol-2-yl]propanedioates. Decarboxylation of the latter compounds resulted in the formation of ethyl 2-13-(dialkoxyphosphory1)-1H-indo1-2-yljacetates. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2997 / 3001
页数：5
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