syn-Selective Aldol Reactions Catalyzed by Praline Methyl Ester under Solvent-Free Conditions

被引：0
|
作者：
Peng, Yiyuan [1 ,2 ]
Cui, Ming [1 ]
Mao, Xuechun [1 ]
Ye, Wei [3 ]
机构：
[1] Jiangxi Normal Univ, Coll Chem & Chem Engn, Jiangxi Key Lab Green Chem, Nanchang 330022, Peoples R China
[2] Jiangxi Normal Univ, Coll Life Sci, Nanchang 330022, Peoples R China
[3] Inst Chem Def, Dept Chem, Beijing 102205, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 30卷 / 03期
关键词：
L-proline ester; organocatalysis; aldol reaction; solvent-free; syn-diastereoselectivity; TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL; ORGANOCATALYTIC CONJUGATE ADDITION; SMALL ORGANIC-MOLECULES; ASYMMETRIC-SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; MANNICH REACTION; EFFICIENT ORGANOCATALYST; ACYCLIC STEREOSELECTION; DIELS-ALDER; PROLINE;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
L-Proline ester catalyzed aldol reaction of cyclopentanone with a variety of aldehdes under solvent-free conditions was investigated. Good to excellent yields with son diastereoselectivity (up to 100% de) were obtained via catalysis by L-proline methyl ester.
引用
收藏
页码：389 / 394
页数：6
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